background: computational identification of phylogenetic motifs helps to understand the knowledge about known functional features that includes catalytic site, substrate binding epitopes, and protein-protein interfaces. furthermore, they are strongly conserved among orthologs, indicating their evolutionary importance. the study aimed to analyze five candidate genes involved in type ii diabetic ...

results the prevalence of micro and macroalbuminuria was 17.2% and 17.6%, respectively. microalbuminuria was significantly associated with longer diabetes duration, increased fasting plasma glucose, and diastolic blood pressure. it was also found that higher plasma glucose and bun (blood urea nitrogen) were risk factors for macroalbuminuria. conclusions prevalence of both micro- and macroalbumi...

accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. to evaluate the association of oxidized low- density lipoprotein (ox-ldl) with the development of diabetic nephropathy, plasma level of ox-ldl were measured in 70 diabetic patients with macro and 63...

the incidence of diabetes mellitus (dm) is increasing rapidly and it is expected to increase by 2030. other than currently available therapeutic options, there are a lot of herbal medicines, which have been recommended for its treatment. herbal medicines have long been used for the treatment of dm because of the advantage usually having no or less side-effects. most of these plants have antioxi...

objective: an association between high homocysteine levels and proteinuria in diabetic nephropathy has been shown. on the other hand, supplementation with folic acid lowers homocysteine concentration. we have studied the effects of folic acid supplementation on proteinuria in type 2 diabetic patients with overt proteinuria. materials and methods: forty five (29 men and 16 women) type 2 diabetic...

objective(s) oxidative stress plays an important role in diabetic nephropathy pathogenesis. rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. material and methods forty male rats were uninephrectomized from the left flank.the rats were divided in four groups randomly; group one as control, group two diabetic untreatment, g...

background: diabetes mellitus is a metabolic disorder and its subsequent complications such as retinopathy, nephropathy, ulcers,disability, and amputation increase the burden of the disease. patient knowledge-improving programs are employed to prevent disease progression and to improve the quality of life of the patients. in this way, we need to characterize the groups of patients in urgent nee...

normal 0 false false false en-us x-none ar-sa background: nowadays vitamin d deficiency is a notable medical condition world-wide and also in iran. since, vitamin d can have reoprotective effect by inhibiting the renin-angiotensin system; it appears that low vitamin d level can worsen the renal injury in diabetic patients. this study demonstrates the effect of vitamin d 3 therapy on reducing pr...

objective: diabetic nephropathy is a major diabetes complication. arterial resistance index (ri) may predict deterioration in kidney function. this study was designed to compare renal arterial ri in different stages of renal function according to glomerular filtration rate (gfr), serum creatinine level and proteinuria. materials and methods: in a cross-sectional study on 81 diabetic patients in...