نتایج جستجو برای: Diazepam

تعداد نتایج: 4065  

Journal: :iranian journal of child neurology 0
p. karimzadeh pediatric neurologist, associated professor, pediatric neurology department, pediatric neurology research center, shahid beheshti university of medical sciences l. afshar khas pediatric neurologist, assistant professor of rafsanjan university of medical scienc a. mosavat pediatric neurologist, assistant professor of pediatrics, rafsanjan university of medical sciences

objective absence status epilepticus (ase) is a common form of nonconvulsive status epilepcticus. it is  characterized by loss of consciousness with spike and wave discharges in eeg simultaneously. the most effective treatment of ase is diazepam, either infusion or in divided doses; the former is more expensive since patients must be admitted in an intensive care unit. the aim of this study was...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2005
Noriaki Sakai Konomu Saito Hyung-Sub Kim Akio Kazusaka Mayumi Ishizuka Yoshihiko Funae Shoichi Fujita

Diazepam was metabolized to three primary metabolites, 3-hydroxy-diazepam, N-desmethyl-diazepam, and p-hydroxy-diazepam. Our previous studies reported metabolic position-specific inter- or intrastrain differences in diazepam metabolism among Sprague-Dawley, Brown Norway, Dark Agouti, and Wistar rats. Especially, there were marked ( approximately 300 fold) inter- or intrastrain differences in di...

Journal: :iranian journal of child neurology 0
afshin fayyazi assistant professor of pediatric neurology, hamedan university of medical sciences, hamedan, iran parvaneh karimzadeh 2. professor of pediatric neurology, pediatric neurology research center, shahid beheshti university of medical sciences (sbmu), tehran, iran 3. professor of pediatric neurology, department of pediatric neurology, mofid children hosptial, shahid beheshti university of medical sciences (sbmu), tehran, iran saadat torabian assistant professor of community medicine, hamedan university of medical sciences, hamedan somayeh damadi general practitioner, hamedan, iran ali khajeh assistant professor of pediatric neurology. children & adolescent health research center, zahedan university of medical sciences, zahedan, iran

how to cite this article: fayyazi a, karimzadeh p, torabian s, damadi s, khaje a. comparison of intravenous midazolam drip with intermittent intravenous diazepam in the treatment of refractory serial seizures in children. iran j child neurol 2012; 6(3): 15-19.   objective serial seizures occur commonly in inpatient epileptic children. this type ofseizure due to its characteristics has a signifi...

Journal: :Pharmacy & pharmacology international journal 2022

Lycium schweinfurthii is found in stony and sandy places belonging to the Solanaceae family which widely distributed North Africa Mediterranean area. The leaves fruits of this plant have traditionally been used for gastrointestinal diseases. This study was aimed evaluate neuropharmacological activity methanolic extract experimental animals. prepared by fractionation technique. Male Albino mice ...

Journal: :The Journal of pharmacology and experimental therapeutics 1983
H E Shannon S Herling

Rats were trained to discriminate between saline and either 0.3, 1.0, 3.0 or 6.0 mg/kg of diazepam in a two-choice, discrete-trial avoidance procedure. Diazepam, chlordiazepoxide, flurazepam and pentobarbital occasioned dose-related increases in diazepam-appropriate responding in all four training dose groups. Increasing the training dose of diazepam from 0.3 to 1.0 mg/kg resulted in approximat...

H HOSSEINI, J AKHONDIAN, M REZAYAT, MS ZARRINDAST, N VAHDATI,

In the present study, the effects of caerulein and CCK receptor antagonist< on tolerance to the anti-pentylenetetrazol activity of diazepam has been studied. Different doses of diazepam (20, 30, 35, 40 and 50 mg/kg) were administered intraperitoneally for a period of 6 days in order to induce tolerance to diazepam. 48 h after the last dose of diazepam, a test dose of diazepam was tested for...

اسدمبینی, عاطفه , حصاری , مهوش , شکیبایی, داریوش, واعظی , مریم,

Background and Objective: Hypothyroidism decreases cardiac contractility and heart rate. Since cardiac function is also modulated by diazepam, the aim of this study was to investigate the direct effect of diazepam on the isolated hypothyroid rat heart. Materials and Methods: This experimental study was conducted on 30 rats in four groups (control, hypothyroid, control diazepam and hypotyroid+d...

Journal: :medical journal of islamic republic of iran 0
m rezayat from the department of pharmacology, tehran and mashhad universities of medical sciences, i.r. iran. h hosseini j akhondian n vahdati ms zarrindast

in the present study, the effects of caerulein and cck receptor antagonist< on tolerance to the anti-pentylenetetrazol activity of diazepam has been studied. different doses of diazepam (20, 30, 35, 40 and 50 mg/kg) were administered intraperitoneally for a period of 6 days in order to induce tolerance to diazepam. 48 h after the last dose of diazepam, a test dose of diazepam was tested for ant...

2010
N. RADOMAN S. IBRIĆ

The study demonstrates two approaches in formulation of solid oral lipid-based diazepam preparations (BCS class II drug). The aim of the study was to formulate tablets and hard capsules, using emulsifier and adsorbent. Lipidbased preparations improve drug solubility and permeability, i. e. bioavailability. Solid silicate carriers are able to adsorb liquid lipid formulations, resulting in freely...

Journal: :Applied sciences 2021

The capacity of natural Na-montmorillonite and activated charcoal for sorption diazepam from simulated intestinal fluid (SIF) was studied. main characteristics the sorbents were determined. In order to characterize process influence pH, contact time ethanol presence in SIF analyzed. Adsorption isotherms diazepam-activated diazepam-natural systems Langmuir isotherm model provided a very good des...

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