نتایج جستجو برای: Dobutamine

تعداد نتایج: 3617  

Journal: :the journal of tehran university heart center 0
hakimeh sadeghian tehran heart center, medical sciences/university of tehran, tehran, iran. masoumeh lotfi-tokaldany tehran heart center, medical sciences/university of tehran, tehran, iran. nader fallah tehran heart center, medical sciences/university of tehran, tehran, iran. seyed hesameddin abbasi tehran heart center, medical sciences/university of tehran, tehran, iran. seyed hossin ahmadi tehran heart center, medical sciences/university of tehran, tehran, iran. abas ali karimi tehran heart center, medical sciences/university of tehran, tehran, iran.

background: this study was designed to investigate the accuracy of dobutamine stress echocardiography (dse) in detecting the post-revascularization recovery rate of contractile reserve (cr) in ischemic myocardium. methods: a total of 112 segments from seven patients with low ejection fraction (<35%) and coronary artery disease were evaluated with dse one week before and 12 weeks after coronary ...

  To detect the effects of sympathomimetic drugs with selective action on β1 and β2 adrenoceptors, male albino mice were treated by intraperitoneal administration of dobutamine and terbutaline for 15 days. Three groups of mice were selected as dobutamine, terbutaline and control groups, respectively. At the end of the experiment, the animals were sacrificed and the parotid glands were removed a...

Journal: :research in cardiovascular medicine 0
satish chandraprakasam division of cardiology, creighton university school of medicine, omaha, nebraska, usa; division of cardiology, creighton university school of medicine, omaha, nebraska, usa. tel: +1-2245326843, fax: +1-4022805967 swapna kanuri division of cardiology, creighton university school of medicine, omaha, nebraska, usa claire hunter division of cardiology, creighton university school of medicine, omaha, nebraska, usa

conclusions the mechanism of mid-variant of dobutamine-induced stress cardiomyopathy remains unclear. we think that multiple mechanisms are involved and this risk should be considered in patients with comorbid psychiatric conditions and with use of centrally acting stimulants. case presentation we report a 48-year-old female with intermittent chest pain. her physical exam, cardiac enzymes and t...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2002
Maohe Yan Leslie T Webster Jeffrey L Blumer

Dobutamine is a synthetic ionotropic catecholamine commonly used to treat heart failure and shock. The catabolic fate of dobutamine in humans has yet to be reported, although formation of 3-O-methyldobutamine represents the principal pathway of dobutamine disposition in the dog. Herein, we describe the isolation and identification of 3-O-methyldobutamine in the urine of children receiving infus...

Journal: :American journal of physiology. Heart and circulatory physiology 2000
K D Yi H F Downey X Bian M Fu R T Mallet

Although the beta(1)-adrenergic agent dobutamine is used clinically to provide inotropic support to the failing myocardium, it could jeopardize the myocardium by depleting energy reserves. This investigation delineated the contractile and energetic effects of low versus high dobutamine doses in the hypoperfused right ventricular (RV) myocardium. The right coronary artery (RCA) of anesthetized d...

Journal: :Journal of the American College of Cardiology 1994
M Ostojic E Picano B Beleslin A Dordjevic-Dikic A Distante J Stepanovic B Reisenhofer R Babic S Stojkovic M Nedeljkovic

OBJECTIVES This study was designed to assess the clinical, hemodynamic and diagnostic effects of the addition of dobutamine to dipyridamole echocardiography. BACKGROUND Pharmacologic stress echocardiography with either dipyridamole or dobutamine has gained acceptance because of its safety, feasibility, diagnostic accuracy and prognostic power. The main limitation of the two tests is a less th...

2014
Gian Maria Pacifici

Dobutamine is a b1 selective stimulant. b Receptor agonists are used to stimulate the rate and the force of cardiac contraction. The chronotropic effect is useful for the treatment of arrhythmias whereas the inotropic effect is useful to augment the myocardial contractility. Dobutamine is about four times as potent as dopamine in stimulating myocardial contractility in low concentrations and in...

2016
JUN YIN QIRONG DONG MINQIAN ZHENG XIAOZU XU GUOYOU ZOU GUOLIN MA KEFENG LI

Dobutamine has been widely used for the treatment of heart failure and cardiogenic shock since the 1970s. Osteosarcoma is the most commonly observed malignant bone tumor in children. Currently, there are no effective drugs for the treatment of osteosarcoma. In the present study, the potential anticancer activity of dobutamine on human osteosarcoma cells was examined. Human osteosarcoma MG-63 ce...

Journal: :Circulation 1983
C Richard J L Ricome A Rimailho G Bottineau P Auzepy

In eight mechanically ventilated patients in cardiogenic shock, we assessed the hemodynamic effects of an infusion of dopamine and dobutamine and evaluated its role in preventing the deleterious effects of administering each amine alone. Each patient received three infusions in a randomly assigned order: dopamine, 15 micrograms/kg/min; dobutamine, 15 micrograms/kg/min; and a combination of dopa...

2003
E Bollano M Scharin Täng

Objective: To determine whether patients with congestive heart failure on different β adrenoreceptor blocking drugs have similar haemodynamic responses to dobutamine. Design: Single centre, single blind, randomised, two period crossover study comparing carvedilol with metoprolol CR/XL. Patients: Ten patients with stable chronic congestive heart failure (ejection fraction < 40%) on chronic treat...

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