objective(s): in this study we evaluate the impact of the different aspects of gold nano-particles (gnps) on the target absorptive dose enhancement factor (def) during external targeted radiotherapy with photon beams ranging from kilovolt to megavolt energies using monte carlo simulation. methods: we have simulated the interaction of photon beams with various energies of radiation using water s...

Background: To enhance the dose to tumor, the use of high atomic number elements has been proposed.Objective: The aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic X-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (GNPs) in the tumor.Method...

background: to enhance the dose to tumor, the use of high atomic number elements has been proposed. objective: the aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic x-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (gnps) in the tumor. meth...

background: gold nanoparticles (gnps) have been shown as a good radiosensitizer. in combination with radiotherapy, several studies with orthovoltage x-rays have shown considerable dose enhancement effects. this paper reports the dose enhancement factor (def) due to gnps in 18 megavoltage (mv) beams. materials and methods: different geometrical 50-nm gnps configurations at a concentration of 5 m...

Background: In neutron interaction with matter and reduction of neutron energy due to multiple scatterings to the thermal energy range, increasing the probability of thermal neutron capture by neutron captures makes dose enhancement in the tumors loaded with these materials. Objective: The purpose of this study is to evaluate dose distribution in the presence of 10B, 157Gd and 33S neutron...

background: in neutron interaction with matter and reduction of neutron energy due to multiple scatterings to the thermal energy range, increasing the probability of thermal neutron capture by neutron captures makes dose enhancement in the tumors loaded with these materials.   objective: the purpose of this study is to evaluate dose distribution in the presence of  10 b ,  157 gd  and  33 s  ne...

Introduction: To enhance the dose to tumor, the use of high atomic number elements has been proposed. Objective: The aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic X-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (GNPs)...

Background: The amount of average dose enhancement in tumor loaded with 10B may vary due to various factors in boron neutron capture therapy.Objective: This study aims to evaluate dose enhancement in tumor loaded with 10B under influence of various factors and investigate the dependence of this dose enhancement on neutron spectra changes.Material and Methods: In this simulation stud...

Background: Gold nanoparticles (GNPs) have been shown as a good radiosensitizer. In combination with radiotherapy, several studies with orthovoltage X-rays have shown considerable dose enhancement effects. This paper reports the dose enhancement factor (DEF) due to GNPs in 18 megavoltage (MV) beams. Materials and Methods: Different geometrical 50-nm GNPs configurations at a concentrati...