Introduction: Dual-modality contrast agents, such as radiolabeled nanoparticles, are promising candidates for a number of diagnostic applications, namely SPECT imaging with MR imaging. So the aim of study was evaluating potential of Chitosan-Coated Magnetic Nanoparticles(SPION) labeled with 99mTc as new Dual-modality probes for liver Imaging. Materials and Methods:</st...

Recent fMRI studies suggest that the inferior frontal sulcus (IFS) is involved in the coordination of interfering processes in dual-task situations. The present study aims to further specify this assumption by investigating whether the compatibility between stimulus and response modalities modulates dual-task-related activity along the IFS. It has been shown behaviorally that the degree of inte...

Dual-modality imaging, using Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) simultaneously, is a powerful tool to gain valuable information correlating structure with function in biomedicine. The advantage of this dual approach is that the strengths of one modality can balance the weaknesses of the other. However, success of this technique requires developing imaging pr...

A novel dual-modality molecular probe composed of biocompatible Fe(3)O(4) nanocrystal, monoclonal antibody and radionuclide was designed and prepared. All functional components in the dual-modality molecular probe, i.e., Fe(3)O(4), PEG, mAb 3H11 and (125)I, were chemically bonded together for forming a stable molecular probe. Systematic in vitro experiments were carried out for evaluating the b...

The present experiment examined the effects of input/output modality pairings on dual-task performance using the psychological refractory period (PRP) procedure. Four groups of participants performed two tasks composed of the same sets of inputs (visual and auditory) and the same sets of outputs (manual and vocal), but with different input/output modality pairings. Whereas modality pairings had...