background: preeclampsia complicates up to 3% of pregnancies in developing countries. endothelial dysfunction plays an important role in pathogenesis of preeclampsia. in this study, we aim to evaluate the effect of low?dose aspirin on endothelial dysfunction in preeclamptic patients. materials and methods: in this triple?blind randomized clinical trial, enrolled patients were divided randomly i...

visit-to-visit variability (vvv) in blood pressure (bp) creates challenges to hypertension control and was independent associated with increased all-cause mortality in hypertensive patients. the major goal of the present study was to investigate the association of vvv in systolic (s)bp with progression of carotid atherosclerosis and en-dothelial dysfunction in on-treated hypertensive patients.o...

background: pre?eclampsia as a hypertensive disorder of pregnancy complicates up to 5–10% of pregnancies worldwide. endothelial dysfunction plays an important role in the pathogenesis of pre?eclampsia. in this study, we aim to evaluate the effect of high?dose folic acid on endothelial dysfunction in pre?eclamptic patients. materials and methods: in this triple?blinded randomized clinical trial,...

conclusions the lack of difference between adma levels in patients with pa and eh suggests that endothelial dysfunction is more likely related to hypertension per se than to the specific etiology of elevated blood pressure. results patients with pa had significantly higher concentrations of adma than healthy controls (0.488 ± 0.085 vs. 0.433 ± 0.053 μmol/l, p = 0.027). no difference was found i...

cardiovascular disease (cvd) is the driving force behind the discrepancy in life expectancy between indigenous and nonindigenous groups in many countries. preceding cvd many indigenous groups exhibit a cluster of cardiometabolic risk factors, including overweight-obesity, diabetes, high cholesterol, and high blood pressure. in turn, modifiable lifestyle risk factors contribute to the developmen...

objective: diabetes is an important risk factor for cardiovascular events. the great percent of morbidity in patients with diabetes is due to endothelial dysfunction. the present study investigated the effects of hydroalcholic extract of nigella sativa (n. sativa)  on contractile and dilatation response of isolated aorta in streptozotocin (stz)-induced diabetic rat. materials and methods: rats ...

conclusions combination of creatine monohydrate and exercise attenuated inflammation and endothelial dysfunction markers among heart failure patients. patients and methods one hundred patients were prospectively randomized into two groups: intervention group which received 5 grams/day creatine monohydrate and exercised for 8 weeks; and control group which did not receive any interventions. inte...

background: aluminum phosphide is the common cause of poisoning in adults in india, with a very high case fatality ratio. we studied five patients of aluminum phosphide poisoning with polyserositis. methods: we enrolled all patients with aluminum phosphide poisoning presenting to emergency medical department, at a tertiary care hospital in northwestern india from january to july 2006. these pat...

background: in most of the studies, the association of vascular events is limited to migraine with aura or it is stronger in this group, whereas the link between migraine without aura (mo) and vascular events remained uncertain. therefore, we decided to evaluate endothelial function by chemical and functional markers of endothelium in mo and compare with normal population. methods: in this stud...