Background: Eosinophilic gastrointestinal disorders or diseases (EGIDs) may result from an abnormal immune-mediated response to food antigens. Activated eosinophils release various mediators with inflammatory properties which may result in tissue and subsequently organ damage. The cytokine milieu of these patients has revealed increased levels of pro-inflammatory cytokines, inc...

Eosinophilic gastrointestinal disorder (EGID) is a rare disease in children that affects the bowel wall, with eosinophilic infiltration in the absence of any other causes for eosinophilia. The etiology remains unknown, but allergies and immunological imbalance are suspected triggers. We encountered a case of serosal EGID presenting as intractable vomiting and ascites in a 9-year-old girl, after...

Eosinophilic gastrointestinal disorders (EGID) are characterized pathologically by excess eosinophils in mucosal biopsies of one or multiple sites in the gastrointestinal (GI) tract, simultaneously or sequentially. Eosinophilic esophagitis (EoE) is the best characterized EGID, and in most patients it is an abnormal immune-mediated response to food antigens. Current recommendations for diagnosis...

Eosinophilic gastrointestinal disorders (EGID) are food allergen-induced allergic gastrointestinal disorders, characterized by accumulation of highly induced eosinophils in different segments of gastrointestinal tract along with eosinophil microabssess and extracellular eosinophilic granules in the epithelial layer. EGID are both IgE- and cell-mediated group of diseases that include eosinophili...

Eosinophilic gastrointestinal disorders (EGID) are rare conditions characterized by eosinophilic infiltration of the bowel wall and gastrointestinal symptoms. These disorders can present with various manifestations, depending on the specific site of the affected gastrointestinal tract and specific layer of the affected gastrointestinal wall. The pathogenesis and etiology of EGID remain unclear....

Background: Eosinophilic gastrointestinal disorders (EGID) are a heterogeneous group of GI disorders, associated with an increase of the eosinophils in the gastrointestinal mucosal tissue. Regulatory T cells (Tregs), as a subset of T cells with proven prominent role in immunopathology and protection against allergic diseases, appear to play a role in EGID pathogenesis. In the present study, ser...

OBJECTIVE Examine treatment adherence rates in pediatric eosinophilic gastrointestinal disorders (EGID). METHODS Participants were children aged 2.5-18 years with eosinophilic esophagitis or eosinophilic gastroenteritis (EGE) and their caregivers. A multimethod, multi-informant assessment including parent report and electronic monitoring was utilized, with a 90% cut point for nonadherence. ...

OBJECTIVE To characterize caregiver stress (CS) in parents of children with Eosinophilic Gastrointestinal Disorders (EGIDs) and understand relationships with psychological functioning and child behavior. METHODS Caregivers with a child (0-17 years) with EGID completed questionnaires for demographics, EGID severity, treatments, CS, psychological distress, self-efficacy, and child behaviors. ...

Background Eosinophilic gastrointestinal disorders (EGID) are clinicopathologically characterized by massive eosinophilic infiltration into the gastrointestinal tract and are classified into eosinophilic esophagitis (EoE), gastritis (EG), gastroenteritis, enteritis and colitis according to the site of infiltration. Studies of the pathogenic mechanism of EoE, whose incidence and prevalence are i...

Eosinophilic colitis (EC) is a rare part of spectrum of diseases called eosinophilic gastrointestinal disease (EGID). It was found to have bimodal distribution involving neonates and adults in age groups of 30 - 50 with male preponderance. We present this case of a 78-year-old woman who came to the hospital with abdominal pain, hematochezia and unintentional weight loss, and was found to have E...