BACKGROUND: Equine herpes virus-1 (EHV-1) is a major cause of economic loss in horse industry and is well recognized as a cause of abortion, respiratory disease, neurologic disorders and death of neonatal foals.OBJECTIVES: The aim of this study was to evaluate the frequency of EHV-1 in horses with clinical signs and/or history associated with this virus from four provinces of Iran (Golest...

The action on mice of several neurotropic viruses was studied with reference to factors which influence infection. With pseudorabies virus, section of the sciatic nerve with inoculation into the ipsilateral foot pad significantly retarded the speed of infection. The virus ascended other nerves of the leg, but at a slower rate. It would appear that the number of nerve fibers available for passag...

Twenty-four species of South African wild animals were tested for the presence of antibodies against the viruses of 16 common diseases of domestic animals. Positive results were obtained for African horsesickness, equine encephalosis, equid herpes virus-1, infectious bovine rhinotracheitis, Allerton disease (Herpes mammillitis), lumpy skin disease, parainfluenza, encephalomyocarditis, bluetongu...

Common viral antigens were detected, by fluorescent-antibody studies, in cells infected with herpes simplex virus 1, squirrel monkey herpesvirus 1, bovine rhinotracheitis, and equine abortion viruses. The two primate viruses showed slight cross-neutralization.

This report describes the first Brazilian equine herpesvirus type 1 (EHV-1) isolation from a single fatal equine herpes myeloencephalopathy case in a mare. The isolation of EHV-1 was confirmed from the first passage of cerebrospinal fluid (CSF) sample in Vero cells by PCR and virus neutralization assay. As virus isolation from CSF is unlikely to be successful, as has been shown in several case ...

An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares comparison with the convention one adjuvanted Al-hydra gel saponin. Such purpose established by 0.5% to EHV-1. The applied quality control tests carried out on such revealed that it is free from foreign contaminants, safe pregnant mice potent indu...

herpes simplex virus type 1 (hsv-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. although hsv type 2 (hsv-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by hsv-1. the present study aimed to discuss the changes in the epidemiology of hsv-1 infection i...

Significant differences exist between the immunogenicity of different commercial vaccines, and these differences should be considered in product selection. It is difficult to identify vaccines that generate significant immune responses to respiratory viruses. Anti-equine herpes virus type 1 (EHV-1) abortion vaccines outperform EHV-1 respiratory vaccines and could be considered for prevention of...

Equine Herpes virus-1 (EHV-1) is one of the most common respiratory pathogens of the horse. EHV-1 induces several clinical signs of disease ranging in severity, from mild respiratory distress to abortion in pregnant mares, neonatal foal death and neuropathogenic disorders. This review details some aspects of EHV-1 biology, its life cycle and pathogenicity in the natural host. Protective immunit...