Introduction: Extreme-altitudes (5500 m/18045 ft and higher) pose environmental, psychophysiological, infrastructural, logistic, and ergonomic challenges that question explorer’s adaptability and mission-efficiency due to isolation, monotony, intimidating environment and terse health conditions. The assessment of an explorer’s comprehensive adaptability in extreme-altitudes is ...

Introduction: Extreme altitude travel has gained popularity globally for adventurous, scientific, and military endeavors. Cerebral venous sinus thrombosis (CVST) at extreme altitude is a rare, covert, and emergent condition requiring immediate intervention. Case Presentation: A case of CVST masqueraded as high altitude cerebral edema (HACE) at 6700 m/22000 ft i...

introduction: extreme altitude travel has gained popularity globally for adventurous, scientific, and military endeavors. cerebral venous sinus thrombosis (cvst) at extreme altitude is a rare, covert, and emergent condition requiring immediate intervention. case presentation: a case of cvst masqueraded as high altitude cerebral edema (hace) at 6700 m/22000 ft in karakoram himalayas. atypical ol...

Department of Physiological Sciences, Medical School, University of Barcelona, Spain Eduardo Garrido Casimiro Javierre Severe mountain sickness, cerebral oedema, or ischaemic infarcts may occur when humans ascend to high altitude. However, neurological symptoms can occasionally be atypical. Recently, we studied a highly experienced climber who had suffered difficulties in expressing himself ver...

Exposure to extreme altitude presents many physiological challenges. In addition to impaired physical and cognitive function, energy imbalance invariably occurs resulting in weight loss and body composition changes. Weight loss, and in particular, loss of fat free mass, combined with the inherent risks associated with extreme environments presents potential performance, safety, and health risks...

The ability of some bird species to fly at extreme altitude has fascinated comparative respiratory physiologists for decades, yet there is still no consensus about what adaptations enable high altitude flight. Using a theoretical model of O(2) transport, we performed a sensitivity analysis of the factors that might limit exercise performance in birds. We found that the influence of individual p...

Increasing numbers of people with diabetes are seeking advice about participation in high altitude climbing, which has the problems of serious metabolic demands, a high likelihood of acute mountain sickness (AMS), and leaving the climber remote from medical care. The American Diabetes Association states that “all levels of exercise, including leisure activities, recreational sports, and competi...