FeCo alloys are an important soft magnetic material because of their unique magnetic properties including large permeability and very high saturation magnetization. FeCo nanoparticles are ideal building blocks for nanostructured thin film or bulk magnetic materials1-3 and are also suitable for biomedical applications.4 However, synthesis of monodisperse FeCo nanoparticles remains a challenging ...

We report here the preparation of Fe, Co, and FeCo nanoplates and nanoparticles by ball milling in the presence of surfactants in organic solvents. By controlling the milling and centrifugation conditions, the Fe, Co, and FeCo nanoplates and nanoparticles with different sizes were successfully obtained, from the slurries and from the top part of the solutions, respectively. The thickness of the...

Among various magnetic nanoparticles that have been studied for potential biomedical applications, FeCo nanoparticles are promising candidates because of their high saturation magnetization and high Curie temperature. [ 3–5 ] However, the ease of oxidation, dissolution in acidic environments, and potential toxicity of these materials in their native state restrict their use in biomedical applic...

Introduction: Inflammation plays a critical role in the progression of atherosclerosis. Novel iron-based nanoparticle platforms may allow noninvasive high-field MRI detection of vascular macrophages in mouse arteries. Purpose: To evaluate two novel nanoparticle platforms – magnetite incorporated human ferritin protein cages (HFn-Fe) and graphite/FeCo core-shell nanocrystals (G-FeCo) – for MRI o...

In this study, we reported a facile synthesis of bimetallic FeCo nanoparticles (Fe-Co NPs) by FeSO4.7H2O and Co(Ac)2.4H2O in the presence of sodium borohydride and 2-thiotic acid. The structure and morphology of the nanoparticles were characterized by X-Ray Diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDS), and Transmission Electron Micros...

BACKGROUND FeCo/graphitic-carbon nanocrystals (FeCo/GC) are biocompatible, high-relaxivity, multi-functional nanoparticles. Macrophages represent important cellular imaging targets for assessing vascular inflammation. We evaluated FeCo/GC for vascular macrophage uptake and imaging in vivo using fluorescence and MRI. METHODS AND RESULTS Hyperlipidemic and diabetic mice underwent carotid ligati...

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A simple and low cost detection of l-cysteine is essential in the fields of biosensors and medical diagnosis. In this study, we have developed a simple electrospinning, followed by calcination process to prepare FeCo nanoparticles embedded in carbon nanofibers (FeCo-CNFs) as an efficient peroxidase-like mimic for the detection of l-cysteine. FeCo nanoparticles are uniformly dispersed within CNF...

In this work, therapeutic magnetic micro carriers (TMMC) guided in real time by a magnetic resonance imaging (MRI) system are proposed as a mean to improve drug delivery to tumor sites. MRI steering constraints and physiological parameters for the chemoembolization of liver tumors were taken into account to design magnetic iron-cobalt nanoparticles encapsulated into biodegradable poly(d,l-lacti...