to follow-up the present study, 40 mature female rats were used. the animals were divided into test,control and sham groups. the rats in the test group were laparotomized and unilateral ovariectomy was done. on the 1st and 2nd met-oestrous after operation, the tissue samples were dissected out and processed for histological study. the intact ovary in the test group underwent a significant (p

Objective Orexin is a hypothalamic orexigenic neuropeptide, which third cerebral injection of it mainly exerts inhibitory effects on reproductive functions. It increases significantly the Aromatase (Cyp19) gene expression in the hypothalamus of male rats. Aromatase is an enzyme which converts androgens to estradiol in the hypothalamus of rats. Prenatal or neonatal exposure of females to testost...

background: nelumbo nucifera has been used as antifertility agent in females by the local tribals of rajasthan especially of udaipur district india. objective: the present study was conducted to investigate the effect of nelumbo nucifera on the fertility and general physiology in female rats. materials and methods: 20 female albino rats were taken and divided into two groups. group 1 served as ...

objective(s): abc transporters comprise a large family of transmembrane proteins that use the energy provided by atp hydrolysis to translocate a variety of substrates across biological membranes. all members of the human abcg subfamily, except for abcg2, are cholesterol-transporter. the aim of this study was to determine the liver, the small intestine and kidney abcg5 relative gene expression i...

previous studies have shown that caffeine has beneficial effects on cognitive impairment in sleep deprived male rats. therefore in the present study, we examined the effects of chronic caffeine administration on learning and memory impairments induced by sleep deprivation (sd) in the intact and ovarectomized (ovx) female rats. two sets of animals including intact and ovx were randomly recruited...

background: the present study examined the possible role of endogenous opioidergic system in effect of food deprivation on formalin-induced nociceptive behaviors in male and female rats. also, we investigated the effect of food deprivation on the plasma level of beta-endorphin and sex hormones. methods: food was withdrawn 48 h prior to performing the formalin test, but water continued to be ava...

objectives the aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (rbcs) indices in diabetic rats. materials and methods peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. results the mean number of whi...

The aim of the present study is a comparative assessment echocardiographic characteristics in female and male mongrel rats. In experiments on anesthetized rats (ketamine 100 mg / kg, iv), it was shown that rats, size volume left ventricle are smaller than males, but compared with their ventricular ejection fraction, which characterizes its inotropic function, statistically significantly higher.

background and objectives: previous studies have shown the antinociceptive effect of morphine in animal models, but the specific anti-pain consequence of the abuse drug in female animals is unclear. the present research showed the morphine antinociception in female wistar rats using formalin test. materials and methods: subjects were 40 female wistar rats purchased from pasteur institute of ira...