five-zone simulating moving bed (smb) system, designed for ternary separation, is a modified form of standard four-zone smb which is only effective in binary separation. it was reported in literature that the five-zone smb separates the extract-ii stream with a lower purity value than that of raffinate and extract-i streams. to address this issue, five zone smb was designed, using safety margin...

Five-zone Simulating Moving Bed (SMB) system, designed for ternary separation, is a modified form of standard four-zone SMB which is only effective in binary separation. It was reported in literature that the five-zone SMB separates the extract-II stream with a lower purity value than that of raffinate and extract-I streams. To address this issue, five zone SMB was designed, using safety ma...

Partial Feed simulating moving bed (SMB) has proved to be more efficient in binary separation performance (purity, recovery, productivity) because of its two additional degrees of freedom, namely feed length and feed time, as compared to classical SMB process. The binary separation of dextran T6 and fructose with linear isotherm is modeled with Aspen Chromatography simulator in a four zone SMB ...

6 Simulated Moving Bed (SMB) processes are widely used in sugar, petrochemical, 7 and pharmaceutical industries. However, systematic optimization of SMB, especially 8 finding the optimal zone configuration including the standard and modified nonstan9 dard configurations, is still a challenging problem. This paper proposes a simultane10 ous, fully discretized approach with an SMB superstructure ...

OBJECTIVE To compare new full-field digital mammography (FFDM) with and without use of an advanced post-processing algorithm to improve image quality, lesion detection, diagnostic performance, and priority rank. MATERIALS AND METHODS During a 22-month period, we prospectively enrolled 100 cases of specimen FFDM mammography (Brestige®), which was performed alone or in combination with a post-p...

The competitiveness of companies increasingly depends upon whether they possess the cutting-edge or core technology. The technology should be protected from industrial espionage or leakage. A special attention needs to be given to SMB (small and medium business), furthermore, because SMB occupies most of the companies but has serious problems in terms of industrial security. The technology leak...

For a pharmaceutical like insulin, the product should be clearly linked to its source. Therefore, it is important to track each batch throughout the production process. Tracking each batch in a simulated moving bed (SMB) process is more challenging than in conventional batch chromatography. Solutes coming from a certain feed batch in SMB can be mixed with solutes coming from adjacent feed batch...

The Staré Město Belt (SMB) in the Central Sudetes forms a Variscan tectonic boundary zone that is located between Saxothuringian and Brunovistulian terranes of Bohemian Massif. three thrust-bounded upper, middle lower lithotectonic units SMB are composed metasedimentary Late Cambrian metavolcanic rocks. A new LA-ICPMS zircon geochronology supported by typology studies mica schists upper unit mi...

Cost-effective isolation methods were developed on preparative HPLC, flash LC, and simulated moving bed (SMB) to prepare the process impurity, 3-(aminomethyl)-5-methylhex-4-enoic acid (4-ene impurity), of pregabalin. By a thorough experimental study on the different isolation techniques available, it was concluded that SMB was the most cost-effective. Hence, it was a continuous chromatography t...