نتایج جستجو برای: Floating in-situ gel

تعداد نتایج: 16999020  

Journal: :the iranian journal of pharmaceutical research 0
rishad r. jivani department of pharmaceutics, smt. r.b.patel mahila pharmacy college, atkot, gujarat, india. chhagan n. patel department of pharmaceutical analysis, shari sarvajanik pharmacy college, mehsana, gujarat, india. dashrath m. patel department of pharmaceutical analysis, shari sarvajanik pharmacy college, mehsana, gujarat, india. nurudin p. jivani department of pharmaceutics, smt. r.b.patel mahila pharmacy college, atkot, gujarat, india.

the present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. fourier transform infrared spectroscopy (ftir) and differential scannin...

Chhagan N. Patel Dashrath M. Patel Nurudin P. Jivani Rishad R. Jivani,

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

Chhagan N. Patel Dashrath M. Patel Nurudin P. Jivani Rishad R. Jivani,

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

Journal: :Pharmaceutical and Biosciences Journal 2019

Journal: :International Journal of Applied Pharmaceutics 2019

2016
G. K. Murthy

The present investigation deals with the formulation, optimization and evaluation of sodium alginate based floating oral In situ gel of Pantoprazole. Sodium alginate used as a polymer and Calcium carbonate was used as a crosslinking agent. In-situ forming polymeric formulation drug delivery systems is in sol form before administration in the body, but once administered, undergoes gelation in-si...

2010
Rishad R. Jivani Chhagan N. Patel Dashrath M. Patel Nurudin P. Jivani

The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

2014
Mohammed Asadullah Jahangir Imran Kazmi Abdul Muheem Kamran Ahmad

Floating drug delivery system provides the advantage of sustained release of drugs over a prolonged period of time thereby maximising the oral absorption of drugs with narrow absorption window, thus, it overcomes the drawback of conventional oral drug delivery system. In situ gelling system is a novel approach in this regard. The aim of the present work was to develop an oral sustained stomach ...

Journal: :Journal of Drug Delivery and Therapeutics 2022

The present research work aimed to formulate and evaluate a gastro retentive in situ gelling system of Nicardipine Hydrochloride using Sodium Alginate as polymer, HPMC K100M release retard calcium carbonate cross-linking agent, tri-sodium citrate fluidity enhancer agent treat hypertension. mechanism for the floatation was based on ionic cross-linking. Several evaluation tests were carried out p...

2013
VADGAMA NEHA BALADANIYA MANOJ

Oral drug delivery is a one of the simplest routes of delivery of drugs for systemic as well as local effect. Liquid oral dosage forms are easy to administer as compared to unit solid dosage forms but sustained effect are not achieved due to less residential time in gastrointestinal tract so,due to this problem In-situ gel used to overcome the problems. The in situ gel dosage form is a liquid b...

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