At CCS 2015, Gueron and Lindell proposed GCM-SIV, a provably secure authenticated encryption scheme that remains secure even if the nonce is repeated. While this is an advantage over the original GCM, we first point out that GCM-SIV allows a trivial distinguishing attack with about 248 queries, where each query has one plaintext block. This shows the tightness of the security claim and does not...

In Drosophila, glial cell differentiation requires the expression of glial cells missing (gcm) in multiple neural cell lineages, where gcm acts as a binary switch for glial vs. neuronal fate. Thus, the primary event controlling gliogenesis in neural progenitors is the transcription of gcm. In addition, gcm is also required for the differentiation of macrophages, and is expressed in the hemocyte...

The glial cells missing (gcm) gene in Drosophila encodes a novel nuclear protein that is transiently expressed early in the development of nearly all glia. In loss-of-function gcm mutant alleles, nearly all glia fail to differentiate, and, where we can follow them in the PNS, are transformed into neurons. In gain-if-function gcm conditions using transgenic constructs that drive ectopic gcm expr...

In this paper we present a fully pipelined high speed hardware architecture for Galois/Counter Mode of Operation (GCM) by analyzing the data dependencies in the GCM algorithm at the architecture level. We show that GCM encryption circuit and GCM authentication circuit have similar critical path delays resulting in an efficient pipeline structure. The proposed GCM architecture yields a throughpu...

The glial cells missing (gcm) gene has been identified as a "master regulator" of glial cell fate in the fruit fly Drosophila. However, gcm is also expressed in and required for the development of larval macrophages and tendon cells. Thus, the Gcm protein activates the transcription of different sets of genes in different developmental contexts. How the Gcm protein regulates these different out...

Measurement of glucocorticoid metabolites (GCM) in faeces has become a widely used and effective tool for evaluating the amount of stress experienced by animals. However, the potential sampling bias resulting from an oversampling of individuals when collecting "anonymous" (unknown sex or individual) faeces has rarely been investigated. We used non-invasive genetic sampling (NIGS) to investigate...

The glial cells missing (gcm) regulatory gene of the sea urchin Strongylocentrotus purpuratus is first expressed in veg2 daughter cells as the genomic target of late cleavage stage Delta-Notch signaling from the skeletogenic mesoderm precursors. Gcm is required in veg2 progeny during late cleavages for the early phase of pigment cell precursor specification. Here we report on a later acting cis...

The physiological role of huntingtin and the pathogenic mechanisms that produce the disease are unknown. Mutant huntingtin changes its normal localization and produces cytoplasmic and intranuclear inclusions, changes gene transcription, alters synaptic transmission, impairs mitochondrial activity and activates caspases and other pro-apoptotic molecules, promotes excitotoxicity, energy deficits,...

The physiological role of huntingtin and the pathogenic mechanisms that produce the disease are unknown. Mutant huntingtin changes its normal localization and produces cytoplasmic and intranuclear inclusions, changes gene transcription, alters synaptic transmission, impairs mitochondrial activity and activates caspases and other pro-apoptotic molecules, promotes excitotoxicity, energy deficits,...

In [9], GSCM mode of operation for authenticated encryption was presented. GSCM is based on the Galois/Counter Mode (GCM). GSCM is an enhancement of GCM, which is characterized by its high throughput and low memory consumption in network applications. In this paper, we propose some enhancements to GSCM and compare it with the different implementations of GCM. We present stability, performance, ...