tribulus terrestris l. var. orientalis (kerner) g. beck is widely used in the traditional medicine of many countries. several flavonoides are identified from the plant material. aerial parts which collected from northeast of iran are used in this study. three flavonoid glycosides were isolated and characterized. the flovonoids were found to be based on quercetin and kaempferol. flavonoid glycos...

ATP, GTP, CoA, Mg(2+), and Mn(2+) did not inhibit biosynthesis of steryl glycoside and acylated steryl glycoside when added singly to enzyme preparations from spinach leaves. The combination of ATP (but not GTP), CoA, and Mg(2+) or Mn(2+) caused marked inhibition, especially of steryl glycoside biosynthesis, when reaction mixture concentrations of the additions were 0.2 millimolar. Inhibition w...

antioxidants are compounds which can prevent biological and chemical substances from oxidative damage by reactive oxygen species. flavonoids are the most important class of polyphenolic compounds that because of their antioxidant characters possess biological activities and pharmacological effects. chrysin-6-c-fucopyranoside and chrysin-3-malonyl-6-c-fucopyranoside are mono c-glycosyl derivativ...

Taxifolin glycoside is a new drug candidate for the treatment of atopic dermatitis (AD). Many drugs cause side effects such as long QT syndrome by blocking the human ether-a-go-go related gene (hERG) K(+) channels. To determine whether taxifolin glycoside would block hERG K(+) channels, we recorded hERG K(+) currents using a whole-cell patch clamp technique. We found that taxifolin glycoside di...

BACKGROUND Steviol glycoside biosynthesis pathway has emerged as bifurcation from ent-kaurenoic acid, substrate of methyl erythritol phosphate pathway that also leads to gibberellin biosynthesis. However, the genetic regulation of steviol glycoside biosynthesis has not been studied. So, in present study RNA interference (RNAi) based Agrobacterium mediated transient gene silencing (AMTS) approac...

Selagin-7-O-(6''-O-acetyl-)-ß-D-glycoside, a new flavone glycoside isolated from Cancrinia discoidea, is known to exhibit anti-inflammatory activity in vivo. This study aimed to investigate the protection of this flavone glycoside on inflammation in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. The effects of selagin-7-O-(6''-O-acetyl-)-ß-D-glycoside on inflammatory cytokines and signali...

BACKGROUND An embryonic toxicity of Rhizoma sparganii was observed in mice. This study was aimed to evaluate the anticancer effects of Grailsine-Al-glycoside, the bioactive component of Rhizoma sparganii, on estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) cancer cell lines. METHODS After A549, HeLa, HepG-2 and MCF-7 cells were treated with Grailsine-Al-glycoside, cell pr...

The release of hydrogen cyanide from endogenous cyanide-containing compounds in plants is an effective herbivore deterrent. We investigated temporal and spatial variations in cyanogenic glycoside concentration in greenhouse-grown seedlings and 6-year-old plantation trees of Eucalyptus cladocalyx F. Muell., which allocates up to 20% of leaf nitrogen to the cyanogenic glycoside, prunasin. The hig...

A flavones glycoside isolated from the bark of ayurvedic plant, Nyctanthes arbortristis was subjected to various pharmacological studies. The glycoside was found to be effective on, cardiovascular system and smooth muscles of intestine but no significant effect was found on CNS. The glycoside exhibited promising anti-inflammatory activity.

A new solanocapsine-type tomato glycoside, a novel and interesting natural steroidal glycoside, was isolated from a mini tomato, Solanum lycopersicum L. The chemical structure of the new minor glycoside, esculeoside B-5 (3), was determined to be (5S,22R,23S,24R,25S)-22,26-epimino-16β,23-epoxy-3β,23,24-trihydroxycholestane 3-O-β-lycotetraoside.