background: radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like developed to date. among the special features of this type of dosimeters, is be doped with other elements or chemicals which made them appropriate for investigating of dose enhancement with contrast agents, by high atomic number. material and methods: in this study...

This study presents the application of the Presage/optical-CT 3D dosimetry system for relative dosimetry in the Radiologic Physics Center (RPC) Head and Neck (H&N) IMRT phantom. Performance of the system was evaluated by comparison with the "gold-standard" RPC credentialing test. A modified Presage cylindrical insert was created that extended the capability of the RPC H&N phantom to 3D dosimetr...

The effects of gold nanoparticles (GNPs) in 125I brachytherapy dose enhancement on choroidal melanoma are examined using the Monte Carlo simulation technique. Usually, Monte Carlo ophthalmic brachytherapy dosimetry is performed in a water phantom. However, here, the compositions of human eye have been considered instead of water. Both human eye and water phantoms have been simulated with MCNP5 ...

Background: Normoxic type MAGICA gel dosimeters are established for dose quantification in three dimensions for radiotherapy. Objective(s): The ability of MAGICA polymer gel was assessed by experimental measurements method for studying the effect of gold nanoparticles (GNPs) in dose enhancement under the external 18MV radiotherapy practices. <...

The aim of the present Monte Carlo study is to evaluate the variation of energy deposition in healthy tissues in the human eye which is irradiated by brachytherapy sources in comparison with the resultant dose increase in the gold nanoparticle (GNP)-loaded choroidal melanoma. The effects of these nanoparticles on normal tissues are compared between 103Pd and 125I as two ophthalmic brachytherapy...

objective(s): in this study we evaluate the impact of the different aspects of gold nano-particles (gnps) on the target absorptive dose enhancement factor (def) during external targeted radiotherapy with photon beams ranging from kilovolt to megavolt energies using monte carlo simulation. methods: we have simulated the interaction of photon beams with various energies of radiation using water s...

PURPOSE In this work, gold nanoparticles (GNPs) were embedded in the MAGIC-f polymer gel irradiated with the 192Ir brachytherapy sources. MATERIAL AND METHODS At the first plexiglas phantom was made as the human pelvis. The GNPs were synthesized with 15 nm in diameter and 0.1 mM (0.0197 mg/ml) in concentration by using a chemical reduction method. Then, the MAGIC-f gel was synthesized. The fa...

introduction: in diagnostic and therapeutic procedures, dosimetric studies are performed on the dosimetric systems in order to comply the radiation safety standards. monte carlo methods are used due to the high complexity and cost of patient-specific phantom construction. the high complexity of the digitized phantoms greatly increases the time and computational task of the monte carlo calculati...