نتایج جستجو برای: HESA-A

تعداد نتایج: 13431798  

Journal: :Entropy 2016
Te-Kang Tsao An-Chou Yeh Chen-Ming Kuo Hideyuki Murakami

The present work investigates the high temperature oxidation and corrosion behaviour of high entropy superalloys (HESA). A high content of various solutes in HESA leads to formation of complex oxides, however the Cr and Al activities of HESA are sufficient to promote protective chromia or alumina formation on the surface. By comparing the oxidation and corrosion resistances of a Ni-based supera...

Journal: :European Journal of Operational Research 2016
Çagri Koç Tolga Bektas Ola Jabali Gilbert Laporte

This paper introduces the fleet size and mix location-routing problem with time windows (FSMLRPTW) which extends the location-routing problem by considering a heterogeneous fleet and time windows. The main objective is to minimize the sum of vehicle fixed cost, depot cost and routing cost. We present mixed integer programming formulations, a family of valid inequalities and we develop a powerfu...

2012
Mehryar Habibi Roudkenar Parisa Bahmani Raheleh Halabian Amaneh Mohammadi oushandeh Ali Jahanian Najafabadi Mohammad Ali Shokrgozar

BACKGROUND Natural medicines have been recently considered more reasonable for human use most notably due to their safety and tolerance. HESA-A is a marine-originated herbal medicine with a variety of healing effects. However, its exact biological mechanism is not clear. The present study aimed at the evaluation of the HESA-A antioxidant effect. METHODS Chinese hamster ovary (CHO) and human e...

2014
Parvaneh Mehrbod Aini Ideris Abdul Rahman Omar Mohd Hair-Bejo

BACKGROUND Influenza virus is still a severe respiratory disease affecting human and other species. As conventional drugs are not recommended for long time because of side effects and drug resistance occurrence, traditional medication has been focused as alternative remedy. HESA-A is a natural compound from herbal-marine origin. Previous studies have reported the therapeutic properties of HESA-...

Journal: :Medical science monitor : international medical journal of experimental and clinical research 2005
Amrollah Ahmadi Mohammad Ali Mohagheghi Mohammad Sadegh Fazeli Bijan Nahavandian Nasrollah Bashardoost Alireza Musavi Jarahi Marjan Gharipoor

BACKGROUND Breast cancer is one of the main causes of mortality among women worldwide. This type of cancer metastasizes to different body tissues, giving rise to many problems. The effect of HESA-A, a drug of herbal-marine origin, on vision, quality of life, and survival of end-stage breast cancer patients was investigated in this study. MATERIAL/METHODS In a double-blind study, 24 breast can...

2017
Shirin Fattahi Sepideh Vosough Hosseini Amir Ala Aghbali Masoumeh Mehdipour Sanaz Helli Hossein Damghani

Background. HESA-A has herbal and marine bases, containing minerals and rare elements such as Zr, Cr, Ga, Mn, Mg, Ca, Sr, Cu, Ti, etc. Its mechanism of action includes antioxidant, antiinflammatory and adjustment of the immune system. The aim of this study was to evaluate the effects of HESA-A systemic drug on expression of cyclin D1, EGFR and E-cadherin in induced tongue dysplasia in rats. Met...

ژورنال: پیاورد سلامت 2012
استاد, سید ناصر, درگاهی, حسین, رستمی, شهربانو, رضایی زاده, حسین, نادعلی, فاطمه, نامجو, سوده, کاظمی, احمد,

Background and Aim: Acute leukemia is one of the main causes of cancer in the world. Now a days using natural materials as source of anticancer drugs is more recommended. HESA-A is a drug of herbal-marine origin (patented by Iranian researcher). HESA-A is composed of 50% inorganic substance، 45% organic substance (aminoenthraquinone) and 5% water. In this study effects of HESA-A، on NB4 cell li...

2016
Nasser Ahmadian Roghiyeh Pashaei-Asl Nasser Samadi Mohammad Rahmati-yamchi Mohammad-Reza Rashidi Masomeh Ahmadian Moosa Esmaeili Faezeh Salamat Sima Besharat Hamid Reza Joshaghani

BACKGROUND Hesa-A is a natural compound with anticancer properties. The exact mechanism of its action in esophageal cancer is not clear, yet. The aim of this study was to evaluate the cell toxicity effect of Hesa-A on the esophageal carcinoma cell lines, KYSE-30, and cell cycle genes expression. METHODS In this study, we tested cell toxicity with MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenylte...

Journal: :basic and clinical cancer research 0
samad muhammmadnejad cancer research center, cancer institute, tehran university of medical sciences, tehran, iran kazem zendehdel cancer research center, cancer institute, tehran university of medical sciences, tehran, iran zohreh mazaheri vali-e-asr reproductive health research centre, tehran university of medical sciences, tehran, iran ahad muhammadnejad cancer research center, cancer institute, tehran university of medical sciences, tehran, iran mahnaz haddadi vali-e-asr reproductive health research centre, tehran university of medical sciences, tehran, iran mohammad-ali mohagheghi cancer research center, cancer institute, tehran university of medical sciences, tehran, iran

background: during the past few years, hesa-a, a herbal-marine mixture, has been used to treat cancer as an alternative medicine in iran. however, weight of the evidence is not sufficient to accept or refuse the use of this compound as a cytotoxic drug. we investigated the selective anticancer effects of hesa-a on breast, prostate, colon, and glioblastoma multiforme (gbm) neoplastic cell lines....

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم پایه 1391

مقدمه: لوسمی لنفوبلاستیک حاد (all) بدخیمی خونی رایجی می باشد که هر دو گروه کودکان وبالغین را مبتلا می کند. جهت درمان آن پروتکلهای شیمی درمانی متعددی وجود دارد که دارای عوارض توکسیک برای بیمار بوده و گاهی منجر به مقاومت دارویی می شوند. با وجود پیشرفت های قابل ملاحظه به دلیل این اثرات جانبی و مقاومت دارویی هنوز درمان ضعیف بوده وبنابراین نیاز به ایجاد درمانهای جدید برای کاهش اثرات سمی می باشد. اثر...

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