The present study was conducted to assess the relationship between chronic kidney disease (CKD) and the homeostasis model assessment of insulin resistance (HOMA-IR) and beta cell function (HOMA-B) in Korean adults with or without type 2 diabetes mellitus (T2DM). This study included 5,188 adults aged 20 or older using the 2015 Korea National Health and Nutrition Examination Survey (KNHANES) data...

OBJECTIVE The homeostasis model assessment (HOMA), based on plasma levels of fasting glucose and insulin, has been widely validated and applied for quantifying insulin resistance and beta-cell function. However, prospective data regarding its relation to diabetes risk in ethnically diverse populations are limited. RESEARCH DESIGN AND METHODS Among 82,069 women who were aged 50-79 years, free ...

Background: Insulin resistance is a major cause for developing type 2 diabetes. However, simultaneously pancreatic beta-cell dysfunction must coexist in clinical occurrence of diabetes (T2D). Hence, knowledge regarding residual function and degree insulin required while treating diabetic patients. Aims Objectives: The present study was done to estimate (homeostatic model assessment - HOMA-IR) f...

BackgroundImpaired insulin sensitivity could be an intermediate step that links exposure to air pollution the development of type 2 diabetes. However, longitudinal associations with remain unclear. Our study investigated long-term degree and rate change sensitivity.MethodsIn this study, we analysed data from Cooperative Health Research in Region Augsburg (KORA) cohort Augsburg, Germany, which r...

INTRODUCTION Gestational diabetes mellitus (GDM) is a heterogeneous disease. We hypothesized that fasting hyperglycaemia, defined as impaired fasting glycaemia (IFG), is a marker of metabolic heterogeneity of GDM. The aim of this study was to compare selected metabolic parameters in two groups of women with GDM, one with normal fasting glycaemia (NFG GDM) and another with IFG, to test this hypo...

<b>Aim:</b> Both obesity and sleep disorders cause chronic subclinical inflammation. Inflammation is a significant factor in triggering insulin resistance. This study aimed to analyze the association between disorders, inflammation, resistance obese/overweight children.<br /> <b>Material methods:</b> In this cross‑sectional study, 150 overweight/obese children were...

BACKGROUND The relative contribution of insulin secretion and sensitivity in the development of type 2 diabetes mellitus (T2DM) vary from population to population due to the heterogeneous nature of the disease. The study was undertaken to evaluate the insulin secretory capacity and sensitivity in a Bangladeshi type 2 diabetic population and to explore the association of some of the anthropometr...

OBJECTIVE To assess whether adolescents with high body mass index (BMI), or fat mass index (FMI), in combination with insulin resistance (assessed with the Homeostatic Model Assessment [HOMA] index), had also lower blood vitamin B6, folate and vitamin B12 concentrations. METHODS AND MATERIALS Six hundred and fifteen adolescents from the Healthy Lifestyle in Europe by Nutrition in Adolescence ...