BACKGROUND There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature. OBJECTIVE We examined the IgE-binding and histamine-releasing properties of hashish and marijuana extracts by CAP-FEIA and a basophil histamine release test. METHODS T...

Drug-metabolizing enzymes play a great role in the bioactivation and also detoxification of zenobiotics and carcinogens such as N-nitrosamines and polycyclic aromatic hydrocarbons (PAHs). Therefore, the present study was undertaken to investigate the effect of narcotic drugs such as cannabis (hashish) and diacetylmorphine (heroin) on the activity of N-nitrosodimethylamine N-demethylase I [NDMA-...

BACKGROUND Enucleation is a topic discussed in psychiatry which is a self-injury matter. Enucleation is observed as psychotic disorder due to substance abuse. In people with mental disorders who also have substance use leading to hallucinations and delusions, unusual eye evacuation were reported. In most cases, enucleation was done using sharp tools. CASE REPORT This report describes a man su...

The volatile constituents of drug samples derived from Cannabis sativa L. were investigated by means of headspace solid phase microextraction (HS-SPME) and gas chromatography techniques (GC-MS, GC×GC-MS). Samples of cannabis herb and hashish showed clear differences in their volatile chemical profiles, mostly resulting from photo-oxidation processes occurring during the transformation of fresh ...

The total concentration of THC has been monitored in cannabis preparations sold in Dutch coffee shops since 1999. This annual monitoring was issued by the Ministry of Health after reports of increased potency. The level of the main psychoactive compound, Delta9-tetrahydrocannabinol (THC), is measured in marijuana and hashish. A comparison is made between imported and Dutch preparations, and bet...

BACKGROUND In less than a decade, Morocco reportedly saw cannabis cultivation decrease by 65%, and hashish production is widely believed to have followed the same trend. Yet large anomalies exist between the alleged fall of hashish production in Morocco and international seizure data. While no explanation for such a discrepancy existed, the main hypothesis was that cannabis cultivation and hash...

BACKGROUND This paper discusses how hashish produced by the local population of Tyup, Kyrgyzstan became an important source of cash in an agricultural semi-subsistence economy. METHODS The paper is based on a research study conducted between 2009 and 2010 that adopted a mixed-method approach to data collection. I gathered 64 semi-structured interviews, 147 structured interviews and made ethno...