background: hemophilia is the most frequent severe hereditary hemorrhagic disease due to deficiency of coagulation factors viii (hemophilia a) or ix (hemophilia b) in plasma. we aimed to identify patients with hemophilia in kermanshah, iran and assess the incidence of inhibitors in this population and its associated factors. methods: this study was conducted on patients with hemophilia a and b ...

conclusions the diagnostics and management of infections with hepatotropic viruses, particularly hbv, are neglected in hemophilic patients. all patients with coagulation disorders and a history of exposure to non-inactivated blood products should be screened for blood-borne infections. the prevalence of other potentially blood-borne viral infections exhibited a pattern similar to that observed ...

background hemophilia might impact the quality of life (qol) in children and adolescent. this study aimed to assess the quality of life in children with hemophilia and identify the factors that predict their qol. methods it was a cross-sectional study. a consensus sample of twenty-seven male children aged 8-16 years old with hemophilia participated in this study during 2011. the haemo-qol quest...

abstract background the purpose of this study was to assess the prevalence of major depressive and anxiety disorders in hemophilic and major beta thalassemic patients related to education of their mothers as a family’s agent. materials and methods a case-control study was performed on 34 major beta thalassemic patients. for each patient the control group was selected and matched (with age and s...

Adriane Fugh-Berman and colleagues describe how strategies similar to those used to market drugs to physicians are directed towards people with hemophilia.

development of inhibitor to factor viii is the most serious complication of hemophilia therapy. to determine the prevalence of inhibitors in iran hemophilia a patients exposed to blood products, 1280 hemophilia a patients (age range 9 months-84 years) were evaluated. all patients received several blood products such as fresh frozen plasma (ffp), cryoprecipitate, and factor viii. 635 of 1280 pat...

1Department of Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA; 2Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON; 3Department of Genetics, University of Pennsylvania, Philadelphia, PA; 4Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC; and 5Department of Pediatrics, University of Pennsylvania, P...

 Of those included, 47.2% were adults, 69.3% had HA and 61.5% had severe hemophilia (HA N=151, HB N=47). Significantly fewer individuals on prophylaxis vs. on-demand treatment were adults, had HB or had mild/moderate hemophilia. (Table 1)  An ABR of 1-10 was recorded in 58% of participants. A higher percentage of adults vs. children with severe hemophilia had ABR ≥11 among those treating on-d...

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