the ethanolic extract of ficus carica leaves was screened for hepatoprotective and antioxidant activity in hepatotoxic albino rats induced via carbon tetrachloride. the degree of protection was measured by estimating biochemical parameters such as serum glutamate oxaloacetate transaminase (sgot), serum glutamate pyruvate transaminase (sgpt), total protein (tp), total albumin (ta), alkaline phos...

The protective effects of oleanolic acid-type saponins and their derivatives on in vitro immunological liver injury of primary cultured rat hepatocytes were studied. A known antihepatotoxic saponin (chikusetsusaponin IVa, 1) showed hepatoprotective activity in this model. Although a rhamnosyl derivative (2) of 1 similarly showed hepatoprotective activity, its prosapogenin (5) did not show any h...

The alcoholic extract of fresh leaves of the plant Eclipta alba (Ea), previously reported for is hepatoprotective activity was fractionated into three parts to chemically identify the most potent bioactive fraction. The hepatoprotective potential of the fraction prepared from extract was studied in vivo in rats and mice against carbon tetrachloride induced hepatotoxicity. The hepatoprotective a...

hepatoprotective efficacy of propolis extract (honeybee hive product, 200 mg/kg, p.o.) was studied against carbon-tetrachloride-(ccl 4, 0.15 ml/kg, i.p.) induced biochemical and histopathological changes. silymarin, a known hepatoprotective drug was used as a positive control. subchronic exposure to ccl 4 for 3 weeks (5 days a week) caused sharp elevation in the activity of liver enzymes i.e. ,...

The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- and paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- and paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination. The plant extract may interfere with free-...

The present study was carried out to evaluate the hepatoprotective role of leaf extracts of Azadirachta indica A. Juss. Hepatoprotective activities of ethanolic and aqueous extracts of A. indica were examined against carbon tetrachloride induced liver damage in mice using silymarin as control. Enzyme activities of Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transa...

Hepatoprotective activity of ethanol extract of Haldinia cordifolia against paracetamol induced hepatic damage in albino rats was observed. In the present study the effect of ethanol extract of Haldinia cordifolia on serum markers such as SGPT, SGOT, ALP and Serum total bilirubin, anti oxidant studies such as SOD, CAT and LPO and Histopathological studies have been studied to find out the possi...

CONTEXT Phyllanthus (Euphorbiaceae) species are traditionally well-known for their medicinal properties including hepatoprotective activity. OBJECTIVE The study assessed the hepatoprotective and antioxidant activities of 11 Phyllanthus species, P. amarus Schumach., P. urinaria L., P. debilis Klein ex Willd, P. tenellus Roxb., P. virgatus G. Forst., P. maderaspatensis L., P. reticulatus Poir.,...

The objective of the present study was to evaluate the phytonutrients, mineral composition, antimicrobial and hepatoprotective activities of leaf of Actinodaphne madraspatanaBedd (A.madraspatana). The content of β-carotene and lycopene in ethanol extract was determined by UV-Visible spectroscopy. The mineral composition of the leaf powder was determined by atomic absorption spectroscopy. The an...

Hepatoprotective efficacy of propolis extract (honeybee hive product, 200 mg/kg, p.o.) was studied against carbon-tetrachloride-(CCl 4, 0.15 ml/kg, i.p.) induced biochemical and histopathological changes. Silymarin, a known hepatoprotective drug was used as a positive control. Subchronic exposure to CCl 4 for 3 weeks (5 days a week) caused sharp elevation in the activity of liver enzymes i.e...