نتایج جستجو برای Histidine

تعداد نتایج: 9395  

Journal: :Biochimica et biophysica acta 1968
D E Hultquist,

I. Phosphorylated derivatives of histidine were synthesized and studied in order to provide a better understanding of the chemistry of phosphohistidine-containing proteins, i-Phosphohistidine, 1,3-diphosphohistidine, a, 1,3-triphosphohistidine, and phosphorylated derivatives of ~-N-acetylhistidine were prepared by reactions with POC13 or phosphoramidate. The compounds were purified by ion-excha...

Journal: :Annals of the rheumatic diseases 1981
J Kirkham, J Lowe, H A Bird, V Wright,

We have compared free serum histidine in patients with rheumatoid arthritis, their blood relatives, and their non-blood relatives. The hypohistidinaemia of rheumatoid arthritis is acquired with the disease and does not provide a biochemical marker of those at risk.

2017
Ulrich Weininger,

Experimental studies on protein dynamics at atomic resolution by NMR-spectroscopy in solution require isolated 1H-X spin pairs. This is the default scenario in standard 1H-15N backbone experiments. Side chain dynamic experiments, which allow to study specific local processes like proton-transfer, or tautomerization, require isolated 1H-13C sites which must be produced by site-selective 13C labe...

Journal: :The Journal of biological chemistry 1959
H G WINDMUELLER, C J ACKERMAN, R W ENGEL,

Since it was shown (2) that the treatment of casein with ethylene oxide could diminish the biological availability of the histidine and methionine of this protein, it became of interest to determine whether other proteins were affected in the same way and to elucidate the nature of the chemical reactions involved. Particular interest in such reactions derives from the use of ethylene oxide as a...

Journal: :Blood 1968
S Krauss, H S Gilbert, L R Wasserman,

E ARLIER OBSERVATIONS of elevated blood and urine histamine levels in myeloproliferative disorders1’2 have recently been confirmed and extended in this laboratory using a sensitive and specific spectrophotofluorometric assay.3 Whole blood and urine histamine content was demonstrated to be increased in uncontrolled polycythemia vera, “spent” polycythemia, and myelofibrosis with myeloid metaplasi...

Journal: :Metal-Based Drugs 1994
J. Xiao, C. Frank Shaw III,

2010
Atsushi ICHIKAWA, Yukihiko SUGIMOTO, Satoshi TANAKA,

Histamine and prostaglandins (PGs) play a variety of physiological roles as autacoids, which function in the vicinity of their sources and maintain local homeostasis in the body. They stimulate target cells by acting on their specific receptors, which are coupled to trimeric G proteins. For the precise understanding of the physiological roles of histamine and PGs, it is necessary to clarify the...

Journal: :Bioscience reports 1989
G C Nikou, Y Yiangou, B J Chrysanthou, J Domin, S R Bloom,

The effect of peptide histidine valine-42 (PHV-42) on gastric acid secretion was studied in man. PHV-42 was infused into 5 healthy volunteers at a dose of 10 pmol/kg/min. This dose caused a significant stimulation of basal gastric acid and potassium output. There were no significant changes in circulating gastrin throughout the infusion. In 2 subjects with a background of submaximal pentagastri...

Journal: :The Journal of biological chemistry 1965
A STRACHER,

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2000
Y Zhu, L Qin, T Yoshida, M Inouye,

Most histidine kinases are bifunctional enzymes having both kinase and phosphatase activities. The cytoplasmic kinase domain of EnvZ, a transmembrane histidine kinase functioning as an osmosensor in Escherichia coli, consists of two distinct functional subdomains: domain A [EnvZc(223-289)] and domain B [EnvZc(290-450)]. NMR studies demonstrated that domain A consists of a four-helix bundle serv...

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