the city centre, Gradually however the crowd thinned slightly, the driver put his foot down and after a certain amount of stuttering and coughing, the ailing vehicle slowly built up speed. Thereafter the driver's technique for dealing with any obstacle was to blow his horn and accelerate towards it. Miraculously the obstacle would melt away at the very last moment, or if it didn't, we simply sw...

In this article, I vindicate the longstanding intuition that Stoics are transitional figures in history of ethics. argue committed to thinking ideal human happiness as a life virtue is impossible for some people, whom dub ‘hopeless fools.’ conjunction with Stoic view everyone subject same rational requirements perform ‘appropriate actions’ or ‘duties’ (kath¯ekonta/officia), and plausible eudaim...

The aim of this study was to determine the association between levels of a marker of oxidative stress, 8-hydroxydeoxyguanosine (8-OHdG), in saliva and the presence of teeth with a hopeless prognosis as a result of advanced periodontitis. Thirty-four periodontitis patients were divided into two groups based on the presence or absence of periodontally-involved teeth of hopeless prognosis. Salivar...

Does bright lighting seem more desirable when people feel hopeless? Common parlance such as ‘‘ray of hope’’ depicts an association between hope and the perception of brightness. Building on research in embodied cognition and conceptual metaphor, we examined whether incidental emotion of hopelessness can affect brightness perception, which may influence people’s preference for lighting. Across f...

End-stage renal failure in an octogenarian with advanced congestive heart failure is a daunting challenge for the physician. Many of these patients cannot tolerate haemodialysis, due to severely impaired left-ventricular function, valvular disease or both. In such patients, peritoneal dialysis may be the only feasible option but home therapy is often impossible, due to age, comorbidity and lack...