persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in nigeria. hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of p. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in wistar rats to substantiate this claim. the chloroform and met...

The effect of hyoscine butylbromide (scopolamine butylbromide), a competitive nonselective antagonist of acetylcholine at muscarinic receptors, on the isolated rabbit duodenum, ileum and colon was investigated. Hyoscine butylbromide (9×10M 9×10M) decreased in a concentration-dependent manner the amplitude of the spontaneous pendular movements of the rabbi-isolated duodenum (r=0.99; p<0.001), il...

Cyclotropium bromide, a new antimuscarinic agent, inhibits gastrointestinal motility in animals at lower doses than those required to inhibit gastric acid secretion and salivation. In man, cyclotropium bromide suppresses fasting and meal stimulated colonic motility. This study investigated the effects of single oral doses of 60 mg cyclotropium bromide, 60 mg hyoscine N-butylbromide and placebo ...

Persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in Nigeria. Hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of P. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in Wistar rats to substantiate this claim. The chloroform and met...

Persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in Nigeria. Hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of P. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in Wistar rats to substantiate this claim. The chloroform and met...

Ten subjects received secretin and cholecystokinin or, in duplicate tests, the two hormones together with either diazepam or diazepam plus hyoscine butylbromide in order to determine whether these drugs, which are often used during retrograde endoscopic cannulation of the pancreatic duct, affect pancreatic and biliary secretion in response to the hormones. Diazepam with hyoscine butylbromide re...

BACKGROUND AND STUDY AIMS Antispasmodics may improve mucosal visualization during colonoscope withdrawal, potentially improving polyp and adenoma detection. Meta-analysis and case-control studies suggest a 9 % to 13 % relative increase in adenoma and polyp detection. We aimed to assess the impact of hyoscine butylbromide on the expected visualization during colonoscope withdrawal using a CT col...

Objective: Hyoscine-N-butylbromide is used by some surgeons during laparoscopic sleeve gastrectomy (LSG) to loosen gastric smooth muscles and provide a more effective LSG. However, evidence-based data on the effects of hyoscine-N-butylbromide in are limited its effect surgery weight loss unknown. The aim this study was analyze intraoperatively administered stomach resection volume, complication...