Hypercholesteremia is one of the risk factors for coronary artery disease. Mushrooms are low calorie food with very little fat and are highly suitable for obese persons. The present study highlights the efficacy of edible mushroom Pleurotus djamor var. roseus extracts on total cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), High density lipoprotein (HDL) and fre...

Objective: Several diseases are reported to be uncommon in those parts of the world where dietary fiber intakes are high, therefore, in this study; we evaluated the hypocholesterolemiceffects of a dietary fiber (guar gum) in hypercholesteromic rats. Materials and Methods: Rats were fed high-fat or a normal fed diet for 12-week then treated with 5% guar gum in their regime during a 28 days peri...

Problem statement: Oxidative stress plays a major role in hypercholesterolemia induced atherosclerosis. Garcinia atroviridis has been shown to exhibit antioxidant properties. Approach: The present study aimed to investigate the effect of Garcinia atroviridis on the oxidative stress in guinea pigs fed with high cholesterol diet. Twenty-four male Guinea pigs were divided into four groups. Group I...

BACKGROUND Klotho is a renal protein with anti-aging properties that is downregulated in conditions related to kidney injury. Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear. METHODS We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein...

Dyslipidemia is major problem among population those have sedentary life style as well as in diabetics. Bougainvillea spectabilis is most commonly found in India as an ornamental plant and has got anti-diabetic action due to presence of one insulin mimicking agent D-pinitol (3-O-methyl-chiroinositol). The present investigation was undertaken to evaluate the effect of alcoholic extract of leaves...

Elevated low-density lipoproteins (LDL) are associated with cutaneous microvascular dysfunction partially mediated by increased arginase activity, which is decreased following a systemic atorvastatin therapy. We hypothesized that increased ascorbate-sensitive oxidant stress, partially mediated through uncoupled nitric oxide synthase (NOS) induced by upregulated arginase, contributes to cutaneou...

The biological activity of the potential therapeutic agent, 80,l 7-epoxy-1 2Elabdene-l5,16-dial (aframodial) 1, has been briefly reviewed. Ten other Cameroonian Aframomum species have been investigated as potentially improved sources for 1 and their aframodial content analyzed. In the course of these investigations three novel diterpenoids, aulacocarpinolide, aulacocarpin A, and aulacocarpin 6,...