نتایج جستجو برای: Hypoxia
تعداد نتایج: 57882 فیلتر نتایج به سال:
macrophages accumulate in poorly vascularised and hypoxic sites including solid tumours, wounds and sites of infection and inflammation where they can be exposed to low levels of oxygen for long periods. up to date, different studies have shown that a number of transcription factors are activated by hypoxia which in turn activate a broad array of mitogenic, pro-invasive, pro-angiogenic, and pro...
objective(s):hypoxia induces cellular oxidative stress that is associated with neurodegenerative diseases. here, the protective effects of ferulic acid (fa) on hypoxia-induced neurotoxicity in pc12 cells were evaluated. materials and methods:we investigated the effect of fa on pc12 cells subjected to hypoxia stress, in vitro. results:fa increased cell viability, prevented membrane damage (ldh r...
Current, lung protection strategy possesses some degree of hypercapnia and hypoxia. Permissive hypercapnia and hypoxia may attenuate the complications of mechanical ventilation in neonates. Adapting this approach and thorough understanding of the biopathologic effects of hypercapnia and hypoxia could prevent mechano-trauma and air leak syndromes. This helps protecting the lung and inflammator...
Objective(s):Hypoxia induces cellular oxidative stress that is associated with neurodegenerative diseases. Here, the protective effects of ferulic acid (FA) on hypoxia-induced neurotoxicity in PC12 cells were evaluated. Materials and Methods:We investigated the effect of FA on PC12 cells subjected to hypoxia stress, in vitro. Results:FA increased cell viability, prevented membrane damage (LDH r...
Background & Aims: Hypoxia and exercise training increase the capillary density of the muscle and the heart and is one of the important reasons for the development of aerobic exercise and the prevention and treatment of many diseases. The purpose of this study was to compare the effects of simulated heights and aerobic training on PGC-1α angiogenesis in the heart tissue. Materials & Methods: T...
hypoxia is a major concern for human health. multiple new techniques were proposed for tissue oxygenation in different variety of patients. clark jr. et al. presenting their article titled “fluorovent: a new perfluorocarbon for liquid ventilation”, at a symposium in neonatology, in 1995, described the scientific importance for perfluorocarbons which would be ideally suited for use in liquid ve...
objective(s): the present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. materials and methods: forty eight wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. animals were placed in a hypoxia chamber and instrumented with epidural catheters at the th...
بررسی اثر کروسین متعاقب ایجاد مدل صرعی با هیپوکسی بر حافظه احترازی و فعالیت حرکتی در موش صحرایی جوان
Background & Aims: Hypoxia is the most common cause of seizures in the neonatal period. Seizure induced by hypoxia cause permanent increases in excitability of neurons and by changing in activity and synaptic plasticity leads to memory impairment. Crocins (Crocus sativus L.) is a water-soluble carotenoid and is the most important active components of saffron. Most studies indicate that crocin h...
Objective(s): The aim of this study is to explore the potential role of hypoxia/reoxygenation in necroptosis in cultured rat renal tubular epithelial cell line NRK-52E, and further to investigate its possible mechanisms.Materials and Methods: Cells were cultured under different hypoxia-reoxygenation conditions in vitro. MTT assay was used to measure the cell proliferation...
Objective(s): The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. Materials and Methods: Forty eight Wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the t...
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