introduction:torch infections causing via toxoplasma gondii, other microorganisms (e.g., treponema pallidum), rubella virus, cytomegalovirus (cmv) and the herpes simplex virus (hsv) types 1 and 2 during the first trimester of pregnancy can lead to severe fetal anomalies or even fetal loss. the current study determined the serological data of torch infections in women who were in their first tri...

objective: a descriptive study was carried out to determine the significance of igg-affinity in the serological diagnosis of rubella infections in pregnancy. materials and methods: a total of 92 pregnant women who had never received antirubella vaccines were recruited by simple random selection and did not exceed 24 weeks of gestation were recruited from the antenatal clinics of the university ...

background: pemphigus is an autoimmune bullous disease and it is unclear what triggers and deteriorates it. the current study aimed to evaluate whether increasing the igg antibody titer represents a good indicator of the pemphigus recurrence. objectives: the current study aimed to evaluate whether increasing igg titer is an indicator of the expected recurrence. patients and methods: the current...

Antibodies are a class of biomolecules that has an important role in the immune system and lots of applications in biotechnological methods and in pharmaceutics. Production and purification of antibodies in laboratory animals is one of the first ways to manufacture of these prominent tools. The obtained antibodies from these process could be used in various types of bioassay techniques such as ...

etiologic factors for recurrent miscarriage (rm) include autoimmune diseases, the most frequently antiphospholipid syndrome and thyroiditis. some women who suffer from rm might also have an altered immune system. we aimed to evaluate possible associations between anti-thyroid and anti-phospholipid antibodies in women with rm. in a retrospective case series 1 on 156 women with rm, major outcome ...

Antibodies are essential tools of biomedical and biochemical researches. Polyclonal antibodies are produced against different epitopes of antigens. Purified F(ab')2 can be used for animal’s immunization to produce polyclonal antibodies. Human immunoglobulin G (IgG) was purified by ion exchange chromatography method. In all stages verification method of the purified antibodies was sod...

Antibodies are a diverse class of glycoproteins that specially bind with antigen and elicit a number of secondary responses in vivo. Most of the applications of antibodies in basic research diagnosis and immunotherapy rely on labeling of the antibody with radiopharmaceuticals. Radiolabeled antibodies are a new class of imaging agents for the detection of sites of disease. True biodistribu...

   Background and aims: Maternal primary and recurrent infection of cytomegalovirus (CMV) may be transmitted to the fetus during pregnancy and may have complications such as death or growth, along with the development retardation of the fetus and infant. The aim of this study was to determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies against CMV in you...

objective(s):human cytomegalovirus (cmv), a double-strand dna herpesvirus, can be transmitted via blood transfusion which is especially important for immunocompromised recipients and can cause a fatal infection. cmv seroprevalence in iran was studied on blood donors, healthy subjects, and some patients. highly variable rates were detected. the purpose of this study was to review cmv seroprevale...

Background: Respiratory Syncytical virus infection is the most common cause of bronchiolitis and viral pneumonia in infancy. Objective: To investigate the placental transfer of RSV-specific IgG in Iranian mothers. Methods: The antibodies were measured in sera of 146 mother/newborn pairs using a commercially available indirect Enzyme Linked Immunosorbent Assay (ELISA). The studied subjects were ...