نتایج جستجو برای: Immunization Against Inhibin

تعداد نتایج: 577315  

Abdalla B Li H Liu Y Mei Ch Shi Zh

Background: The objectives of a series of studies undertaken was to improve farm animal reproductive efficiency in terms of embryo production efficiency, conception rate and litter size by immunoneutralization of inhibin in conjunction with other conventional reproductive techniques. Materials and Methods: A recombinant porcine inhibin alpha-subunit mature peptide was produced by mass scale and...

Journal: :The Journal of endocrinology 2003
M S Medan G Watanabe K Sasaki Y Nagura H Sakaime M Fujita S Sharawy K Taya

This study was conducted to evaluate the effect of active immunization against inhibin on hormonal levels and the ovulation rate in goats. Ten adult Shiba goats (Capra hircus) in two groups were used in this study. The first group was injected with inhibin vaccine (immunized, n=5) and the second group was injected with Freund's adjuvant (control, n=5) followed by three booster injections at 4-w...

2005
E. T. Setiatin M. Bryant

Inhibin is released during late prophase by suppressing the FSH secretion without affecting LH secretion. Immunization against inhibin will increase FSH synthesis leading to ovulation rate. As both immunization against inhibin and FSH injection could increase ovulation rate, therefore, an interaction of both treatment should act synergically or addively. Immunized group (n=10) were immunized wi...

Journal: :Theriogenology 2003
J E Wheaton R W Godfrey

Active immunization against inhibin has been shown to advance puberty and increase ovulation rate in ewe lambs; but in ram lambs, effects on puberty and sperm production are equivocal. The objective of the present study was to determine whether active immunization against an inhibin alpha-subunit peptide advances the onset of puberty in ram lambs. St. Croix hair sheep ram lambs were assigned to...

Journal: :Endocrine journal 2000
F Shi K Mochida O Suzuki J Matsuda A Ogura C G Tsonis G Watanabe A K Suzuki K Taya

Embryo recovery and subsequent embryonic development from guinea pigs treated with or without inhibin vaccines were compared to determine the effect of active immunization against the inhibin alpha-subunit. Twenty female guinea pigs of the Hartley strain were injected 3 times either with 1 ml inhibin vaccine (recombinant ovine inhibin a-subunit in oil emulsion: 50 microg/ml, inhibin-immunized g...

Journal: :The Onderstepoort journal of veterinary research 2000
C R Sewani-Rusike C Dakwa

Inhibin is a gonadal hormone that inhibits the release of follicle stimulating hormone (FSH) from the anterior pituitary gland. The objective of this study was to determine whether active immunization of male and female rats against inhibin rich, steroid-free bovine follicular fluid would increase inhibin antibody titre, onset of female puberty, pregnancy rate, litter size, testis weights, test...

Journal: :Journal of animal science 2007
J L Voge J E Wheaton

The gonadal hormone inhibin regulates daily sperm production (DSP) indirectly through negative feedback control of FSH secretion and may also affect DSP via direct actions within the testis. Studies attempting to increase DSP through the immunization against inhibin have yielded equivocal results. The current study compared 2 inhibin antigens for effects on DSP and hormone secretion. Hampshire ...

Journal: :The Journal of reproduction and development 2006
Mohamed S Medan Toshiro Takedom Yoshito Aoyagi Masato Konishi Shigeto Yazawa Gen Watanabe Kazuyoshi Taya

The hypothesis of the present study is that active immunization of cows against inhibin would neutralize endogenous inhibin, increase circulating levels of follicle stimulating hormone, and subsequently affect follicular dynamics and the ovulation rate during the estrous cycle. Thirteen cows were immunized against inhibin alpha-subunit and, 6 cows were immunized with a placebo. Both groups were...

Journal: :Journal of animal science 1991
R L Meyer K M Carlson J Rivier J E Wheaton

A synthetic fragment representing the N-terminal 25 amino acid residues of the alpha-subunit of ovine inhibin (alpha-IF) was coupled to human alpha-globulin (h alpha-G) and used as an antigen. In Exp. 1, ovine antiserum generated against alpha-IF-h alpha-G was shown in vitro to neutralize inhibin bioactivity contained in ovine follicular fluid. In Exp. 2, 18 lambs were immunized with .3, .6 and...

Journal: :Journal of animal science 1991
B D Schanbacher

Prepubertal crossbred beef bulls served as controls or were actively immunized against the N-terminal, 30-amino acid synthetic fragment of porcine inhibin alpha, pI alpha (1-30). Antibody titers were detected in sera (greater than 40% B/BO in sera diluted 1,000-fold) but not in rete testis fluid of 390-d-old bulls. Serum FSH and inhibin remained static during a 5-h intensive bleed; inhibin was ...

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