background: mesenchymal stem cells (mscs) possess a wide range of immunomodulatory functions mostly in immune cells including dendritic cells (dcs). dcs are the key cells in the immune response and play an important role in initiating cell-mediated immunity. objective: to evaluate the immunomodulatory effects of mscs supernatant on maturation and function of dcs. methods: bone marrow derived mi...

background: oral aphthous is one of the most common oral mucosal inflammatory disorders which are very painful. there is no definite medical strategy up to now for aphthous treatment. recently, some researchers have focused on immunomodulatory drugs such as tacrolimus and pimecrolimus in preventing aphthus recurrences. the aim of this study is to assess the effect of pimecrolimus cream against ...

multiple sclerosis (ms) is the most common chronic autoimmune demyelinating disorder of the central nervous system (cns) which preferentially involves young women in early child bearing age. opposite to traditional view emphasized on discouraging female patients from enduring pregnancy, recent investigations showed that pregnancy-related physiological alterations, especially during the third tr...

1 Department of Psychoimmunology, National Institute of Psychiatry “Ramón de la Fuente”, Calzada México-Xochimilco 101, Colonia San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexico 2 Research Group Immunophysiology, Institute of Physiology and Pathophysiology, Philipps University, 35037 Marburg, Germany 3 Instituto de Inmunologı́a, Facultad de CienciasMédicas, UniversidadNacional de Rosa...