background: salvia mirzayanii, a native plant to iran, is shown to have immunomodulatory effects on lymphocyte proliferation. objective: to identify the bioactive immunomodulatory compound(s) present in s. mirzayanii. methods: the crude extract was fractionated to five fractions in two steps using different solvents. the fractions were subjected to bioassay-guided fractionation. all the fractio...

introduction: lithium salts are known as effective psychotropic medicine for treatment bipolar disorder and may be used to treat alcoholism, schizoaffective disorders, and cluster headaches. the antioxidant activity and immunomodulatory effects of prospective lithium compounds have been investigated in this work. materials and methods: the antioxidant properties were studied by the voltammetry ...

four known flavonoids: quercetin 3-o-β-d-rutinoside (q3rut), myricetin 3-o-β-d-galactopyranoside (m3gal), quercetin 3-o-β-d-galactopyranoside (q3gal) and quercetin 3-o-β-d-glucopyranoside (q3glc), for the first time were isolated from aerial parts of euphorbia microsciadia. the chemical structure of them was elucidated on the basis of 1 and 2 d-nmr spectra and different spectroscopic techniques...

objective: homalium letestui pellegr (flacourtiaceae) is used in traditional medicine in parts of nigeria for the treatment of malaria, ulcer, and inflammatory diseases and as an aphrodisiac. this investigation was aimed to evaluate the cytotoxic, immunomodulatory, and antileishmanial properties of stem extract and fractions of homalium letestui (h. letestui). materials and methods: cytotoxic a...

objective: vernonia amygdalina (v.  amygdalina) leaf is locally employed in the southern region of nigeria in the treatment of malari a infection. this study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of v.  amygdalina leaf. materials and methods: the active principles of the dried leaf were extracted with ethanol. for quality validation, ch...

nephrotoxicity is a major side effect of cisplatin, a widely used chemotherapy agent. morphine and other opioids are also used extensively in different types of cancer for the clinical management of pain associated with local or metastatic neoplastic lesions. in addition to its analgesic effects, morphine has also been reported to possess potential immunomodulatory and antioxidant properties. h...

objective(s):gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. in this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. materials and methods: three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (ip) for the evaluation o...