immunoproliferative small intestinal disease (ipsid) is the syndrome associated with mediterranean lymphoma (a rare form of non-hodgkin’s lymphoma). many of the patients diagnosed with secretory ipsid have variable level of abnormal immunoglobulins in serum or other bodily fluids, identified as truncated alpha heavy chain globulins. most cases are characterized by a loss of ability to synthesiz...

Immunoproliferative small intestinal disease (IPSID) is the syndrome associated with Mediterranean lymphoma (a rare form of non-Hodgkin’s lymphoma). Many of the patients diagnosed with secretory IPSID have variable level of abnormal immunoglobulins in serum or other bodily fluids, identified as truncated alpha heavy chain globulins. Most cases are characterized by a loss of ability to synthesiz...

RATIONALE Chronic diarrhea in adult patients due to various causes is very common in clinic, but patient suffering with mal-absorption due to immunoproliferative small intestinal disease was rarely reported in China. PATIENT CONCERNS AND DIAGNOSES A 35-year-old female presented with more than three years history of chronic diarrhea, rickets, high serum value of immunoglobulin A protein, and a...

During the period of 1984-1995, nine young patients were admitted to Shiraz University Hospitals with a chief complaint of abdominal mass, weight loss and chronic diarrhea. Clinically, these cases were diagnosed as intestinal tuberculosis or lymphoma. Laparotomy revealed a huge mass involving the upper small intestine. Histologic sections showed diffuse infiltration of the intestinal wall w...

during the period of 1984-1995, nine young patients were admitted to shiraz university hospitals with a chief complaint of abdominal mass, weight loss and chronic diarrhea. clinically, these cases were diagnosed as intestinal tuberculosis or lymphoma. laparotomy revealed a huge mass involving the upper small intestine. histologic sections showed diffuse infiltration of the intestinal wall with ...

heavy chain disease, mediterranean lymphoma, and immunoproliferative small intestinal disease

intestinal tuberculosis is an uncommon presentation of tuberculosis (tb) and has clinicopathological similarities with crohn's disease. in regions where tb is endemic clinicians must aware of this condition and fully evaluate their patients when crohn's disease is diagnosed. we recommend all pathologic specimens be evaluate effectively for tb.smear,culture and pcr for mycobacterium.tuberculosis...

BACKGROUND Immunoproliferative small intestinal disease (also known as alpha chain disease) is a form of lymphoma that arises in small intestinal mucosa-associated lymphoid tissue (MALT) and is associated with the expression of a monotypic truncated immunoglobulin alpha heavy chain without an associated light chain. Early-stage disease responds to antibiotics, suggesting a bacterial origin. We ...

156 Iranian patients with primary malignant tumors of the small intestine were reviewed. Malignant lymphoma was the most common tumor type, comprising 128 patients (82%), followed by adenocarcinoma (22 patients, 14.1 %), leiomyosarcoma (4 patients, 2.56%) and carcinoid tumor (2 patients, 1.28%). Lymphomas and adenocarcinomas were primarily located in the duodenum or jejunum, whereas leiomy...