introduction: differentiation between infection and sterile inflammation is one of the most difficult medical problems and is relevant in many clinical situations. scintigraphy with radiolabeled antibiotics, еspecially labeled fluoroquinolones, is a promising tool for diagnosing bacterial inflammation. we have attempted to synthesize 99mtc-norfloxacin and studied its properties in experiment. m...

introduction: full crown preparation may have adverse effects on pulp tissue. in this study, the effect of full-crown preparation on intact versus inflamed pulp tissue was studied. methods: fifteen healthy mature cats were randomly selected for this study. the study was performed on four canine teeth of each cat. cats were anesthetized and then radiographs were taken from the canine teeth. clas...

multiple sclerosis (ms) is a chronic inflammatory demyelinating disease of the central nervous system that inflammation, demyelination, oligodendrocyte loss, gliosis, axonal injury and neurodegeneration are the main histopathological hallmarks of the disease. although ms was classically thought as a demyelinating disease, but axonal injury occurs commonly in acute inflammatory lesions. in ms mi...

statement of the problem some studies reveal that pregnancy can be considered to be a risk factor for periodontal disease, due to increased levels of estrogens and progesterone. propose of this study was to determine oral health changes during pregnancy, using the community periodontal index for treatment needs (cpitn). material & methods this descriptive cross-sectional study was done on 95 pr...

objective: asthma is a chronic inflammatory disease of the respiratory airways distinguished by edema and infiltration of inflammatory immune cells. to test our hypothesis about the anti-inflammatory effect of saffron, we examined effects of crocus sativus (c. sativus) extract as a prophylactic anti-inflammatory agent in sensitized rats. materials and methods: to induce experimental asthma, rat...

background & aim: pap smear is a screening procedure for cervical cancer. the incidence and mortality rate of cervical cancer has decreased up to 90% in the regular screening in women aged 20-65 years. this study aimed to investigate the pap smear reports of pathology laboratories in ahvaz, iran. methods: in this cross-sectional study, 1,006 pap smear reports were collected from pathology labor...

background smoking is an established risk factor for cardiovascular diseases and metabolic syndrome. objectives here we aimed to assess the effect of 3-month aerobic training on c-reactive protein (crp) level and total antioxidant capacity (tac) in male smokers. results aerobic training resulted in a significantly increased tac (p < 0.001), but crp remained unchanged (p = 0.96). conclusions des...

in inflammatory diseases such as peri-implantitis (pi) and chronic periodontitis (cp) both adaptive and innate immunity play a part. natural resistance associated macrophage protein 1 ( nramp1 ) has considerable effects on macrophage function (phagocytosis) and host innate immune response against infections. the present study was to investigate the relationship of nramp1 gene polymorphisms with...

cortical spreading depression (csd) are associated with dramatic failure of brain ion homeostasis, efflux of excitatory amino acids from nerve cells, increased energy metabolism and changes in cerebral blood flow. there is strong clinical and experimental evidence to suggest that csd is involved in the mechanism of migraine, stroke, subarachnoid hemorrhage and traumatic brain injury. therefore,...

introduction: the aim of the present study was to evaluate the effect of oxytocin on the angiogenesis and inflammatory parameters in air pouch model of inflammation. methods: inflammation was induced by injection of carrageenan into pouches in male wistar rats. oxytocin (4.25, 8.5 and 17 μg) was administered intra pouch at the same time as the carrageenan and then for 2 consecutive days. after ...