objective(s): inflammation is an immune response toward injuries. although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, alzheimer’s and various cancer. indonesian cassia (cinnamomum burmanni c. nees & t. ness) known to contain coumarin, is widely used for alternative medicine es...

background: erythrocyte sedimentation rate (esr) is one of the predictors of improvement in handling rheumatoid arthritis. this study was designed to define and compare the time of achieving normal esr and also the percentage for the normalization of this marker at several points of time in two different combination therapies.methods: fifty-two rheumatoid arthritis patients randomly received me...

background: hemodialysis patients are at greater risk of cardiovascular disease. higher than expected cardiovascular morbidity and mortality in this population has been attributed to dislipidemia as well as inflammation. the causes of inflammation in hemodialysis patients are multifactorial. several markers were used for the detection of inflammatory reaction in patients with chronic renal dise...

how to cite this article: ghanizadeh a, berk m. beta-lactam antibiotics as a possible novel therapy for managing epilepsy and autism, a case report and review of literature. iran j child neurol. 2015 winter;9(1):99-102. abstract autism is a disorder of unknown etiology. there are few fda approved medications for treating autism. co-occurring autism and epilepsy is common, and glutamate antagoni...

background : propylene glycol (1,2-propanediol, pg) is a commonly used solvent for oral, intravenous, as well as topical pharmaceutical preparations. while pg is generally considered to be safe, it has been known that large intravenous doses given over a short period of time can be toxic. objective: to evaluate the effect of pg in sepsis induced by the bacterial endotoxin lipopolysaccharide (lp...

objectives: inflammation is a common complication in patients treated with hemodialysis and increasing in inflammatory factors such as c-reactive protein (crp) is associated with increased cardiovascular disease and mortality in these patients. the purpose of this study was to investigate the effect of oral l- carnitine supplementation on serum crp concentration and fasting blood sugar (fbs) in...

background: protein energy malnutrition and inflammation in hemodialysis (hd) patients often leads to the malnutrition inflammation complex syndrome or atherosclerosis malnutrition and inflammation related to the atherosclerotic cardiovascular disease.   this syndrome occurs in patients undergoing dialysis for a long time and is accounted as an important factor of mortality among these patients...

background and objective: regarding side effects of acute and especially chronic inflammation and incomplete treatment of patients suffering from these side effects, the new and effective strategies are needed. for this purpose, in the present study, we scientifically evaluate an introduced folk herb urtica dioica, for treatment of inflammation. materials and methods: the sham, control and trea...

Many mammalian AQPs, including AQP1, AQP2, AQP4, AQP5 and AQP8, function primarily as bidirectional water-selective transporters. Cells expressing AQPs on their plasma membrane have an ~5- to 50-fold higher osmotic water permeability than membranes that do not. Water transport through single-file pores poses a biophysical limitation on the efficiency with which AQPs can transport water, so that...

Inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, UV radiation, stress and etc. Persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from T cells. These molecules (e.g. IL-6, TNF-&alpha, IL-1&beta and IL-17) are mostly pleiotropic cytokines i...