a:4:{s:10:"Background";s:504:"While the etiology of PCOS has continued to remain a mystery, there can be found some evidence in support of the presence of chronic low-grade inflammation in women with this syndrome. One of the most significant manifestations of chronic inflammation is Pro-inflammatory cytokines. Therefore, the aim of this prospective study was to investigate the pattern of proinfla...

TNFα is one of the most important inflammatory cytokines which induces caspase and apoptotic process. There are two forms of TNFα: soluble TNFα (solTNFα) and transmembrane TNFα (tmTNFα). These inflammatory cytokines have two receptors namely TNRF1 and TNRF2. The attachments of the cytokines to those receptors induce the TRAF and activate the NK-Kb. TNFR1 is f...

Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...