نتایج جستجو برای: Insilico
تعداد نتایج: 253 فیلتر نتایج به سال:
Black cumin (Nigella sativa) is a spice having medicinal properties with pungent and bitter odour. It is used since thousands of years to treat various ailments, including cancer mainly in South Asia and Middle Eastern regions. Substantial evidence in multiple research studies emphasizes about the therapeutic importance of bioactive principles of N. sativa in cancer bioassays; however, the exac...
With more than 500,000 genomic profiles freely available in the public domain, there is a huge amount of information accessible for computational biologists or bioinformaticians. However, accessibility to these data requires complex computational steps. Manual parsing of annotations and keywords, which is in most cases a necessary evil, tends to be time-consuming and is known to be error-prone....
Conventionally, drugs were discovered by synthesizing compounds in a time-consuming multi-step processes against a battery of in vivo biological screens and further investigating the promising candidates for their pharmacokinetic properties, metabolism and potential toxicity. Sophisticated insilico approaches has given a tremendous opportunity to pharmaceutical companies to identify new potenti...
Insilico structural analysis of an immunotherapeutic glycoprotein T11TS (sheep CD58) a b b c b a
The epigenetics of methylated and unmethylated DCR1 DCR2 (decoy receptors 1 2) are genes encoding membrane that can bind to TRAIL causing inhibition in the apoptotic pathway. Epigenetic detection was developed as a biomarker breast cancer. One methods is using PCR. most important step PCR process determination annealing temperature. This research performs Tm analysis insilico program from Neb, ...
The authors thank OpenEye Scientific Software Inc., ChemAxon, and Cepos Insilico Ltd. for providing Academic Licences for ROCS, JChem, and PARASURF, respectively. This work is funded by the Agence Nationale de la Recherche, grant reference ANR-08-CEXC-017-01. VIPN is grateful for a Marie Curie IEF Fellowship. A) The target structures were first superposed onto the crystallographic query using P...
A new drug takes a long time and is expensive to introduce.By using insilico design, you can save money. Utilizing computational software, novel Schiff's base Dibenzosuberenone derivative was designed molecular docking studies were performed autodock software. To predict Absorption, Distribution, Metabolism, Excretion, Molecular Properties of derivatives, screening performed. It should be exami...
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