نتایج جستجو برای: Interleukin-29

تعداد نتایج: 234934  

Amir Hossein Taromchi Bahram Kazemi, Mojgan Bandehpour, Sanaz Mahmazi

Background: Interferons with diffrent functions such as antiviral, antiproliferative and immunomodulatory actions are effctive <span style="font-varia...

Journal: :The Egyptian Journal of Hospital Medicine 2023

Journal: :Gut 1994
K M Lammers J Jansen P B Bijlsma M Ceska G N Tytgat C L Laboisse S J van Deventer

Interleukin 8 is a neutrophil chemotactic and stimulating cytokine induced by various inflammatory stimuli, including tumour necrosis factor, interleukin 1, and endotoxin. The ability of HT 29/19A enterocytes to synthesise interleukin 8 was studied. The results show that interleukin 1 is an important stimulus for interleukin 8 synthesis and secretion by HT 29/19A cells, being more potent than t...

Journal: :Blood 2009
Jihong Dai Nicholas J Megjugorac Grant E Gallagher Raymond Y L Yu Grant Gallagher

IFN-lambda1 (IL-29) plays a novel, emerging role in the inhibition of human Th2 responses. Here, we demonstrate that both naive and memory human CD4(+) T cells express mRNA for the IFN-lambda1-specific receptor, IL-28Ralpha, and are responsive to IFN-lambda1. Expression of Th2 cytokines (IL-4 and IL-13) was suppressed in naive and memory CD4(+) T cells by IFN-lambda1, without affecting their pr...

2016
Lingxiao Xu Qiuyue Peng Wenhua Xuan Xiaoke Feng Xiangqing Kong Miaojia Zhang Wenfeng Tan Meilang Xue Fang Wang

We have recently shown that IL-29 was an important proinflammatory cytokine in pathogenesis of rheumatoid arthritis (RA). Inflammation also contributes to the pathogenesis of osteoarthritis (OA). The aim of this study was to investigate the effect and mechanism of IL-29 on cytokine production and cartilage degradation in OA. The mRNA levels of IL-29 and its specific receptor IL-28Ra in peripher...

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