This study aimed to investigate tourniquet-induced compartment syndrome of the limb, consequential development multiple organ dysfunction syndrome, and its counteraction with pentadecapeptide BPC 157 therapy.

Ischemia-reperfusion injury is a serious problem which can occur during lung transplantation. Preservation of pulmonary function by reducing ischemia-reperfusion injury is essential for successful lung transplantation. Although the mechanisms responsible for ischemia-reperfusion lung injury are not clear yet, it is commonly accepted that ischemic time, storage conditions and additive usage of s...

Introduction: It has been reported that traumas such as transverse abdominal incision before myocardial ischemia result in a significantly decreased infarct size. This phenomenon is named remote preconditioning of trauma. Since small skin burn is one of most common traumas, the effect of this injury on ischemia-induced arrhythmias and infarct size was investigated in a rat model of ischemia-rep...

Purpose: To study the effect of dexmedetomidine (Dex) on myocardial ischemia-reperfusion injury (MIRI), and associated mechanism action.Methods: Sixty Sprague-Dawley (SD) rats were assigned to sham, (I/R), Dex, MD groups (methyllycaconitine prior injection with Dex), 15 in each group. Pathological changes tissues determined all groups. Protein expression levels HMGB1, TLR4, NF-κB myeloid differ...

Background CMR is the imaging modality of choice to quantify myocardial injury in studies of cardioprotection. Remote ischemic conditioning (RIC), using transient limb ischemia and reperfusion, is a novel therapeutic intervention, which can protect the heart against acute ischemiareperfusion injury (IRI). Whether RIC can reduce myocardial infarct (MI) size, and improve myocardial salvage in ST-...

Introduction: It has been reported that traumas such as transverse abdominal incision before myocardial ischemia result in a significantly decreased infarct size. This phenomenon is named remote preconditioning of trauma. Since small skin burn is one of most common traumas, the effect of this injury on ischemia-induced arrhythmias and infarct size was investigated in a rat model of ischemia-...