background: the sperm count and function may be affected by karyotype abnormalities or microdeletion in y chromosome. these genetic abnormalities can probably transmit to the children. objective: in this study, we tried to determine the frequency of karyotype abnormalities and y chromosome microdeletions in severe oligospermic or azoospermic men who fathered sons by icsi. materials and methods:...

Indigofera santapaui Sanjappa is little-known species and reported from very few localities of the north Western Ghats. In present investigation, somatic chromosome number (2n=16) karyotype analysis were for first time in I. santapaui. The formula was observed to be 2n=16=12m+4sm. Karyotype fell 2B asymmetric category Stebbins’ classification.

the karyotype of pike from anzali lagoon in the south caspian sea basin have been investigated by examining metaphase chromosomes spreads obtained from gill epithelial and kidney cells. the chromosomes spreads were stained with 7% giemsa solution for 15 min and examined under a light microscope. appropriate metaphase plates were photographed in order to prepare karyotype. all specimens had a di...

chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and g banding techniques. the chromosomes diploid number was 2n= 64 and polymorphism of three type chro...

We investigated whether karyotype analysis and mutational screening by next generation sequencing could predict outcome in 101 newly diagnosed chronic lymphocytic leukemia patients with high-risk features, as defined by the presence of unmutated IGHV gene and/or 11q22/17p13 deletion by FISH and/or TP53 mutations. Cytogenetic analysis showed favorable findings (normal karyotype and isolated 13q1...

In this study, for the first time in Iran, the karyotype of bigmouth Lotak, Cyprinion macrostomum Heckel, 1843, was investigated through examining metaphase chromosomes of seven fish with mean weight 30±5g caught by electrofishing from Godarkhosh River in Ilam Province. To stimulate cell divisions, fish were injected intraperitoneally two times by phytohemagglutinin (PHA). The cell divisions we...

Genetic aberrations contribute to acute myeloid leukemia (AML). However, half of AML cases do not contain the well-known aberrations detectable mostly by cytogenetic analysis, and these cases are classified as normal karyotype AML. Different outcomes of normal karyotype AML suggest that this subgroup of AML could be genetically heterogeneous. But lack of genetic markers makes it difficult to fu...