background: melaleuca cajuputi essential oil in aerosol spray was evaluated against the dengue vectors aedes ae­gypti and ae. albopictus at low cost housing flats in section 10, setapak, kuala lumpur, malaysia. methods: essential oil in aerosol viz: 5% and 10% of concentrations were sprayed for 5 seconds each towards hung mos­quitoes in 5 cylindrical net cages. aerosol weights were recorded bef...

curcumin is a natural substance with anti-cancerous properties without many disadvantages of currently-used anticancer drugs. its toxicity is significantly higher in tumor cells compared with normal cells. we hypothesized the difference of p53 function between normal and tumor cells as one of the presumable causes of this phenomenon. we knocked down the expression of p53 in normal fibroblasts u...

Objective(s): A growing body of evidence indicates that rhomboid domain containing 1 (RHBDD1) plays an important role in a variety of physiological and pathological processes, including tumorigenesis. We aimed to determine the function of RHBDD1 in breast cancer cells. Materials and Methods: In this study, we used the Oncomine™ database to determine the expression patterns of RHBDD1 in normal a...

Background: Despite recent advances in diagnosis and treatment, breast cancer remains a leading cause of death in women worldwide. Long non-coding RNAs are a new class of RNA molecules that have been shown to participate in tumorigenesis. The aim of this study was to investigate the expression of lncUSMycN in tumor samples and to evaluate its potential role in the breast cancer cell line. Metho...

Riemerella anatipestifer is a duck pathogen that has caused serious economic losses to the duck industry worldwide. Despite this, there are few reported studies of the physiological and pathogenic mechanisms of Riemerella anatipestifer infection. In previous study, we have shown that TonB1 and TonB2 were involved in hemin uptake. TonB family protein (TbfA) was not investigated, since knockout o...

Background: Tumor radioresistance leads to a reduction in the efficiency of radiation therapy. It is very important to explore the cellular mechanisms leading to radioresistance and to find potential therapeutic targets, which might improve the efficacy of radiation therapy. This study was to investigate the role of ataxia-telangiectasia mutated (ATM) and murine double minute X (MDMX) in radior...