Lipid phosphate phosphatases (LPPs) are a group of enzymes that belong to a phosphatase/phosphotransferase family. Mammalian LPPs consist of three isoforms: LPP1, LPP2, and LPP3. They share highly conserved catalytic domains and catalyze the dephosphorylation of a variety of lipid phosphates, including phosphatidate, lysophosphatidate (LPA), sphingosine 1-phosphate (S1P), ceramide 1-phosphate, ...

It has been established recently that, under mild conditions, deterministic long run average problems of optimal control are “asymptotically equivalent” to infinite-dimensional linear programming problems (LPPs) and that these LPPs can be approximated by finite-dimensional LPPs. In this paper we introduce the corresponding infiniteand finite-dimensional dual problems and study duality relations...

We establish that deterministic long run average problems of optimal control are “asymptotically equivalent” to infinite-dimensional linear programming problems (LPPs) and we establish that these LPPs can be approximated by finite-dimensional LPPs, the solutions of which can be used for construction of the optimal controls. General results are illustrated with numerical examples.

This study aimed to examine the mechanism for differential effects of low- (LPPS) and high-phosphorus (HPPS) potato starches and high-amylose cornstarch (HACS) on rat cecal fermentation, the n-butyrate proportion in particular. In ileorectostomized rats, the in vivo resistant starch (RS) contents were determined to be 66% (LPPS), 66% (HPPS) and 36% (HACS), but the carbohydrate/nitrogen (C/N) ra...

BACKGROUND Effective anticancer drug delivery to the tumor site without rapid body clearance is a prerequisite for successful chemotherapy. 1,2-distearoyl-sn-glycero-3-phospho-ethanolamine-N-(methoxy[polyethyleneglycol]-2000) (DSPE-PEG2000) has been widely used in the preparation of stealth liposomes. Although PEG chains can efficiently preserve liposomes from rapid clearance by the reticuloend...

Late positive potentials (LPPs) were found to be decreased during down-regulation and increased during up-regulation of positive and negative emotions. However, previous studies lack ecological validity, since they explicitly instructed their participants to use certain regulation strategies. The goal of our study was to test an ecologically more valid paradigm of emotion regulation. We therefo...

Evaluation of soil quality can be crucial for designing efficient farming systems and ensuring sustainable agriculture. The present study aimed at evaluating the quality of waterlogged purple paddy soils with different productivities in Sichuan Basin. The approach involved comprehensive analyses of soil physical and chemical properties, as well as enzyme activities and microbial community struc...

Lipid phosphate phosphatases (LPPs) are a class of enzymes that can dephosphorylate a number of lysophopholipids in vitro. Analysis of knockouts of LPP family members has demonstrated striking but diverse developmental roles for these enzymes. LPP3 is required for mouse vascular development while the Drosophila LPPs Wunen (Wun) and Wunen2 (Wun2) are required during embryogenesis for germ cell m...

In the present study we have characterized mammalian sphingosine-1-phosphate phosphohydrolase (SPP1), an enzyme that specifically dephosphorylates sphingosine 1-phosphate (S1P) and which differs from previously described lipid phosphate phosphohydrolases. Based on sequence homology to murine SPP1, we cloned the human homolog. Transfection of human embryonic kidney 293 and Chinese hamster ovary ...

Mariculture products are generally deemed to have less negative environmental externalities and more nutrient content, therefore a promising food substitute for land-based protein (LPPs). China is the world's largest mariculture producer, with 66% of global production share in 2018. However, different categories varied composition impacts, ignoring such heterogeneity potentially misleads policy...