objective(s) annual incidence of cutaneous leishmaniasis is increasingly growing and development of the alternative drugs against it is a major concern. artemisia genus is a traditional medicinal plant in iran. the aim of this study was to examine the leishmanicidal activity of various iranian artemisia species extracts. materials and methods different extracts were gathered from eleven iranian...

due to the limited availability of effective pharmaceutical products and serious side effects of the available therapy for leishmaniasis, search for useful medicinal plants is necessary. previous studies reported preventative effect of echinacea against leishmania infections through immunologic stimulation. here we tested concentrated ethanolic extract of the root of echinacea purpurea prepared...

Leishmania donovani, an intracellular protozoan, causes kala-azar by parasitizing the macrophages of its mammalian host. Outbred NCS and CD-1 mice develop immunity to this parasite. This immunity was demonstrable when supernatant fluids from cultured splenic lymphocytes were added to infected macrophages. Only the lymphokine preparations from infected mice showed significant leishmanicidal acti...

OBJECTIVES Annual incidence of cutaneous leishmaniasis is increasingly growing and development of the alternative drugs against it is a major concern. Artemisia genus is a traditional medicinal plant in Iran. The aim of this study was to examine the leishmanicidal activity of various Iranian Artemisia species extracts. MATERIALS AND METHODS Different extracts were gathered from eleven Iranian...

Objective(s) Annual incidence of cutaneous leishmaniasis is increasingly growing and development of the alternative drugs against it is a major concern. Artemisia genus is a traditional medicinal plant in Iran. The aim of this study was to examine the leishmanicidal activity of various Iranian Artemisia species extracts. Materials and Methods Different extracts were gathered from eleven Iran...

background: the leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. methods: essential oils were obtained by the steam distillation of plant leaves without any prior processing. cytotoxicity was tested on j774 macrophages and leishmanicidal activity was assessed against four species of leishmania associated with cutaneous leishmaniasis ....

BACKGROUND The leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. METHODS Essential oils were obtained by the steam distillation of plant leaves without any prior processing. Cytotoxicity was tested on J774 macrophages and leishmanicidal activity was assessed against four species of Leishmania associated with cutaneous leishmaniasis. ...

Purpose: To evaluate the leishmanicidal and cytotoxic activity of alcohol and non-alcohol extracts and saponins from Ilex laurina. Methods: Extracts were obtained by percolation with solvents of different polarities: hexane, dichloromethane, ethyl acetate and ethanol. The ethyl acetate extract was subjected to silica gel column chromatography eluting with a step gradient of dichloromethane-meth...