نتایج جستجو برای: Leukotrienes
تعداد نتایج: 4437 فیلتر نتایج به سال:
This paper reviews the leukotrienes, a new group of biologically active compounds in the metabolism of eicosapolyenoic acids. The leukotrienes are acyclic eicosanoids that arise through the 5-lipoxygenase pathway from eicosatrienoic, eicosatetraenoic, and eicosapentaenoic acid. Of these eicosatetraenoic acid, arachidonic acid, is the most important source of leukotrienes. Leukotriene B4 (LTB4),...
PURPOSE OF REVIEW This review will critically highlight the role of leukotrienes as mediators of renal diseases and drug nephrotoxicity. It will also discuss the recently identified mechanism of cysteinyl leukotrienes induction and action, and will propose clinical implementation of these findings. RECENT FINDINGS Since last reviewed in 1994, leukotrienes were shown to mediate drug-associated...
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