Activation of peroxisome proliferator-activated receptor (PPAR)-α which regulates lipid metabolism in peripheral tissues such as the liver and skeletal muscle, decreases circulating lipid levels, thus improving hyperlipidemia under fasting conditions. Recently, postprandial serum lipid levels have been found to correlate more closely to cardiovascular diseases than fasting levels, although fast...

OBJECTIVE To explore whether or not statins have any impact on the progression of components of benign prostatic hyperplasia (lower urinary tract symptoms severity, prostate volume and serum prostate specific antigen (PSA) when combined with other agents inhibiting growth of prostate cells. MATERIALS AND METHODS This was a preliminary, clinical study. Eligible patients were aged > 50 yrs, wit...

Background: Ischemic stroke is quite heterogeneous in its patho-physiological mechanism associated withatherosclerosis. Little known about measures for prevention of the disease apart from latest technologies andmedications.Method: 100 patients different age groups were studied with MRA, to rule out occlusion or lesion; tropicaldistribution infarction, clinical manifestations, recurrence after ...

Postprandial hyperglycemia is well established as a major risk factor for prediabetes and type 2 diabetes. However, postprandial hyperlipidemia, no definitive criteria exist, fasting values of lipids lipoproteins had limited efficacy estimating lipidemia. In the present study, we performed fat-ingestion test aimed to propose indices lipoprotein metabolism. Methods: Healthy young Japanese women ...

Background Multimorbidity is highly impactful for older adults, especially when it co-occurs with Alzheimer’s disease (AD). However, scarce evidence available about comorbid conditions co-occurring AD. We aimed to identify the most prevalent and examine common multimorbidity patterns in patients Method Using electronic health records of a university hospital, we extracted data from 2,646 adults...