in the september and november 2006 issues of nature clinical practice nephrology , two articles regarding living unrelated kidney donor transplantation alluded to the practices in iran. having served in the planning, supervision and implementation of various aspects of health care in iran, including organ transplantation (anh), and as transplant nephrologists who have actively participated in t...

Background: The Presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. However, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. Objective: To study microchimerism in a group of kidney transplant recipi...

background: the presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. however, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. objective: to study microchimerism in a group of kidney transplant recipi...

introduction although renal transplantation from cadaver is common, living donors continue to be an important source of transplanted kidneys. recipients of living-donor kidneys demonstrate improved graft survival. in this study, we evaluated the outcomes of renal transplantation from cadaver, related donors and unrelated donors in isfahan. methods we evaluated all of the patients who underwent ...

background: in addition to human leukocyte antigens (hla) compatibility, gene polymorphisms in cytokines might also be important in the quality of allogeneic immune response. objective: to evaluate the influence of hla-dr matching and a number of cytokine gene polymorphisms on acute rejection after living-unrelated donor (lurd) kidney transplantation. methods: a total of 42 renal transplants pe...

patients and methods from march 1976 to december 2013, the number of patients that underwent living renal transplantation sharing at least one hla haplotype with their donors was 2,485. we divided these patients into two groups: (1) 2,075 kidney transplant recipients (1,554 or 74.9% male and 521 or 25.1% female) for whom the donors were living related, (2) 410 kidney transplant recipients (297 ...

background& objective:  the prevalence and annual incidence of end stage renal disease  among 60 million iranians is about 15000 and 3175 (53 patients per million), respectively. the first renal transplantation was performed in shiraz, iran in 1967. iran has the most successful renal transplant program in the middle east  region. the renal transplant activity of the country has reached 24 renal...

conclusions we found acceptable short-term survival in both groups; however, living donor recipients continue to have better long-term patient and graft survival rates. results although there were no significant differences in one-year survival rates of patient and graft between study groups, three-years survival rates of patient and graft were significantly longer in living donor kidney transp...