Iodine deficiency remains a major health problem in the world, including some parts of Iran. It has been recognized that there is usually a close and inverse relationship between iodine in the soil and water and presence of endemic goiter. Calcium has been suggested as one of goitrogens, though the definite role, extent and mechanism particularly in human have not been studied. Serum protein-...

The purposes of the study were to assess knowledge, self-efficacy, and perceived barriers on a low-iodine diet among thyroid cancer patients and to identify strategies for nutrition education. A self-administered questionnaire was developed based on a review of literature and pilot-tested. A total of 121 female thyroid cancer patients participated in a survey and 117 responses were used for dat...

The present studies demonstrate that iodine depletion increases the sensitivity of the thyroid to the goitrogenic effects of thyrotropin. Iodine depletion was induced by feeding rats a low iodine diet containing propylthiouracil for 10-14 days before hypophysectomy. Accumulation of iodine in the thyroid after hypophysectomy was prevented by continuing the antithyroid drugs in the diet. Doses of...

The Philippines is one of the countries where adequate iodine status has been achieved. However, iodine deficiency still remains an important public health problem in this country. In this study, we evaluated iodine nutrition status and investigated an awareness status of iodine deficiency targeting high school students of Tuguegarao, Philippines. A total of 260 students provided samples for ur...

Is the fetal thyroid already capable to increase its iodide uptake in response to iodine deficiency? To answer this question, we analyzed the expression of the Na(+)/I(-) symporter and several other genes in the thyroid of rat fetuses at 21 d of gestation from control mothers presenting a mild or more severe iodine deficiency. Female rats were placed on a low iodine diet, not supplemented, or s...

Introduction: A low iodine diet (LID) is recommended prior to the Radioactive Iodine-131 (RAI) treatment or scanning in differentiated thyroid carcinoma (DTC) post total thyroidectomy. However, recommended strictness of LID is varying among major guidelines. This study was aim to investigate the patient’s compliance to LID by measuring the urinary iodine level post LID. <...

The last 2 decades it has become clear that iodine deficiency has a modulating effect on the thyroid autoimmune response in humans. Also, in animals that spontaneously develop autoimmune thyroid disease, evidence is accumulating that a low iodine intake can modulate thyroid autoimmune reactivity. However, it is still not clear what the effect of a low iodine intake on thyroid autoimmune reactiv...

It is the present acceptance in general that the level of dietary iodine is of paramount importance for the proper working of the thyroid gland. Remington low iodine diet is much used for studies on iodine deficiency in rats. This diet induces the hyperactive state of the thyroid gland, which is proved by the increase of I131 uptake and thyroid/serum radioiodide concentration ratio(T/S ratio)or...

background: this study aimed to assess several biochemical and oxidative stress parameters before and after radioiodine therapy in patients with well-differentiated thyroid cancer who consumed a low iodine diet and withdrawal of levothyroxine after total thyroidectomy. methods: we enrolled 40 candidates for radioiodine therapy. blood sampling was performed prior to as well as 72 h after consump...