background: an increase in the number of intraepithelial lymphocytes (iel) in the duodenal mucosa is an important criterion for the histological diagnosis of celiac disease (cd). we determined the normal range for intraepithelial lymphocytes (iel) in the second part of duodenum in healthy iranian population. materials and methods: four biopsy samples of the endoscopically normal appearing mucos...

background: various responses and different prognosis to specific treatment in different patients from one hand, and importance of ifn-γ producer cells on the other hand impressed us to study tc1. methods: the study was conducted in ghaem medical center and bu-ali research institute, mashhad university of medical sciences, iran from 2001 to 2002. lymphocytes of 36 patients were counted and cult...

objective: common variable immunodeficiency (cvid) is one of the most frequent cases of primary immunodeficiency. it is likely that this heterogeneous disease is caused by several distinct genetic disorders. the activation-induced cytidine deaminase (aid) enzyme is involved in class switching, somatic hypermutation (shm) and processes associated with gene conversion in the germinal center. in o...

unresponsiveness to hepatitis b surface antigen (hbsag) has been shown to be associated with dysfunction of the presenting cells (apc) and defect in the specific b-lymphocyte and/or t-lymphocyte repertoires.   direct determination of the frequency of specific t-lymphocytes together with complementary analysis of the naive circulating immune cells could provide valuable information about the cel...

background : now a days researchers have shown grean interest in electromagnetic waves which spread from devices such az microwaves,satellites,tv,cell phones etc,due to various reports of their devasting effects on animal growth and health.in this study the effects of these radiations on blood cells is investigated . methods : in the present study the effect of radiation on blood parameters in ...

background coronary heart disease (chd) is the leading cause of death worldwide. research indicates that coronary atherosclerosis is the most frequent cause of chd. evidence is scarce concerning the clinical efficacy of fibrinogen or neutrophil-lymphocyte ratio (nlr) measurement in risk-stratifying patients with chronic stable angina. conclusions nlr and fibrinogen predicted cad, independent of...

background: similar to inflammatory cells, peripheral blood mononuclear cells (pbmcs) can also infiltrate in to kidney and urinary tracts and subsequently excreted by urine. in this study we determined the viability rate and response to phytohemagglutinin-a (pha) of human pbmcs in normal urine. methods: a number of 1×106 ficoll-hypaque isolated pbmcs were dispensed in 1 ml normal urine and 6 mo...

despite many advances in the treatment of breast cancer, it is still the second most common cause of death in women in the united states. it has been shown that inflammation plays a major role in the treatment of these cancers and inflammatory factors enhance tumor growth, invasion, metastasis, and vascularization. in this study, we would like to analyze peripheral blood neutrophil-lymphocyte r...

Introduction: Obesity is an increasing health problem in the whole world, and it has important inflammatory component related to insulin resistance (IR), hypertension, atherosclerosis some cancers. This study aims evaluate hematological parameters childhood obesity.Methods: Sixty-four obese 50 normal weight cases were included study. The physical examination features laboratory data of patients...