BACKGROUND To investigate influencing factors of the metastatic lymph nodes ratio (MLR) and whether it is related to survival in patients with gastric adenocarcinoma. METHODS We retrospectively evaluated the clinical features of 121 patients with gastric adenocarcinoma enrolled in our hospital between 2000 and 2007. The receiver operating characteristic (ROC) curve was used to determine the c...

BACKGROUND The middle latency response (MLR) can be a powerful tool for assessing integrity of cortical and subcortical auditory structures. Most research on the MLR, however, is constrained to relatively slow repetition rates by the time window necessary for response acquisition. Maximum length sequence (MLS) paradigms enable the recording of the MLR at high repetition rates, which could reduc...

The phenotypic expression of I-region determinants on cells producing and responding to MLR suppressor factor (MLR-TsF) was established in these studies. Alloantigen-activated MLR suppressor T cells (MLR-Ts), which produce MLR-TsF bearing gene products of the I-C subregion, were exposed to anti-I subregion sera and complement (C) before in vitro culture for MLR-TsF production. Suppressor activi...

2(1H)-pyrimidinone,5-(3-methylphenoxy) (MLR-1023) is a candidate for the treatment of type 2 diabetes. The current studies were aimed at determining the mechanism by which MLR-1023 mediates glycemic control. In these studies, we showed that MLR-1023 reduced blood glucose levels without increasing insulin secretion in vivo. We have further determined that MLR-1023 did not activate peroxisome pro...

The mesencephalic (or midbrain) locomotor region (MLR) was first described in 1966 by Shik and colleagues, who demonstrated that electrical stimulation of this region induced locomotion in decerebrate (intercollicular transection) cats. The pedunculopontine tegmental nucleus (PPT) cholinergic neurons and midbrain extrapyramidal area (MEA) have been suggested to form the neuroanatomical basis fo...

This report describes a Ts costimulator assay and its use to analyze cofactors required for the expression of suppressor T cell function. Activation of primed MLR-Ts (alloantigen-activated suppressor T cells suppressive of mixed leukocyte reaction) to suppressor T cell factor (TsF) production typically fails in the presence of glutaraldehyde-fixed rather than irradiated allogeneic stimulator ce...

We have previously described the activation of a population of mixed leukocyte response suppressor T cells (MLR Ts) 1 by H-2-incompatible leukocytes. Reexposure of such cells to priming H-2 alloantigens in vitro triggers the release of a suppressor factor (MLR TsF) that prohibits alloantigen-induced T cell proliferation in the mixed leukocyte response (MLR) (1). Activated MLR Ts and MLR TsF cha...

Basics 5 Learning Tasks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Task types and creation . . . . . . . . . . . . . . . . . . . . . . . 5 Further settings . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Accessing a learning task . . . . . . . . . . . . . . . . . . . . . . 10 Modifying a learning task . . . . . . . . . . . . . . . . . . . . . . 13 Example tasks a...

PURPOSE The monocyte-to-lymphocyte ratio (MLR) has been shown to be associated with the prognosis of various solid tumors. This study sought to evaluate the important value of the MLR in ovarian cancer patients. METHODS A total of 133 ovarian cancer patients and 43 normal controls were retrospectively reviewed. The patients' demographics were analyzed along with clinical and pathologic data. ...

BACKGROUND Availability of user-friendly statistical software has increased the application of multivariable logistic regression (MLR) in the medical journal many fold. The reporting quality in terms of checking assumptions, model building strategies, proper coding, and report format need proper care and attention to communicate correct and reliable model results. OBJECTIVE The objective of t...