نتایج جستجو برای: MRC-5 cell

تعداد نتایج: 2710949  

Journal: :research in pharmaceutical sciences 0

sirtuin1 (sirt1) is an enzyme that deacetylates histones and several nonhistone proteins including p53 during stress and plays an important role in the survival of tumor cells. hereby, this study describes the potency of salermide as a sirt1 inhibitor to induce apoptosis in the mcf-7 and mrc-5 cell lines. mcf7 and mrc-5 cell lines were cultured in rpmi-1640 and treated with or without salermide...

Journal: :iranian journal of pathology 2008
massoud hajia abbas mahmoodzadeh hassan morovati

background and objective: pneumocystis pneumonia (pcp) has been historically the most prevalent opportunisticinfection in patients infected with the human immunodeficiencyvirus. culture of the organism has not been faced with suitable success in artificial media, while various results have been reported for cell culture media. the aim of this study was proliferation of pneumocystis carinii on t...

Journal: :iranian journal of cancer prevention 0
abbas zare mirakabadi dept. of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran ali sarzaeem dept. of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran

background: our previous studies revealed an inhibitory effect of icd-85 (venom derived peptides) on mda-mb231 and hl-60 cell lines, through induction of apoptosis. the purpose of this study was to investigate apoptosis-induced mechanism on hela and mrc-5 cells by icd-85 through activation of caspase-8. methods: cell viability, cytosolic enzyme lactate dehydrogenase (ldh) and cell morphology we...

M Lotfi , M Taghavian , MK Shahkarami , S Soleimani ,

Background and Aims: Adventitious agents, especially viral agents are among the most important concerns in viral vaccines. Viral contamination of biological products may arise from the original source of the reagents such as, serum, trypsin, animal or human derived media components or cell culture and working seed or cross contamination of vaccine during production. In this study, adventitious ...

2018
Song-Ming Ding Ai-Li Lu Wu Zhang Lin Zhou Hai-Yang Xie Shu-Sen Zheng Qi-Yong Li

Background: Our previous study showed that cancer-associated fibroblast MRC-5 promoted hepatocellular carcinoma progression by enhancing migration and invasion capability. However, few studies have explored the role of MRC-5 in pancreatic cancer (PC). In this study, we examined the exact role and associated mechanisms of MRC-5. Methods: The conditioned media for MRC-5 was used to culture PC cel...

Abbas Mahmoodzadeh Hassan Morovati Massoud Hajia,

  Background and Objective: Pneumocystis pneumonia (PCP) has been historically the most prevalent opportunisticinfection in patients infected with the human immunodeficiencyvirus. Culture of the organism has not been faced with suitable success in artificial media, while various results have been reported for cell culture media. The aim of this study was proliferation of Pneumocystis carin...

Journal: :iranian journal of virology 0
s soleimani department of viral vaccine quality control, razi vaccine and serum research institute, karaj, iran m lotfi department of viral vaccine quality control, razi vaccine and serum research institute, karaj, iran m taghavian department of human viral vaccine, razi vaccine and serum research institute, karaj, iran mk shahkarami department of human viral vaccine, razi vaccine and serum research institute, karaj, iran

background and aims: adventitious agents, especially viral agents are among the most important concerns in viral vaccines. viral contamination of biological products may arise from the original source of the reagents such as, serum, trypsin, animal or human derived media components or cell culture and working seed or cross contamination of vaccine during production. in this study, adventitious ...

Journal: :Microbiology 2002
Gregory J Tyrrell Alexander Kennedy Sandra E Shokoples Richard K Sherburne

The interactions of group B streptococci (GBS) with HeLa cells (an epithelial cell line) and MRC-5 cells (a fibroblastic cell line) were explored. A host-cell invasion assay using GBS strains from all serotypes revealed that GBS invaded HeLa cells to a greater extent than MRC-5 cells. One strain, a serotype V (NCS13), was highly invasive against HeLa cells. All strains were poorly invasive agai...

2013
M Nikbakht Dastjerdi M R Salahshoor M Mardani M Rabbani B Hashemibeni M Gharagozloo M Kazemi N Esmaeil Sh Roshankhah R Golmohammadi M Mobarakian

Sirtuin1 (SIRT1) is an enzyme that deacetylates histones and several nonhistone proteins including p53 during stress and plays an important role in the survival of tumor cells. Hereby, this study describes the potency of salermide as a SIRT1 inhibitor to induce apoptosis in the MCF-7 and MRC-5 cell lines. MCF7 and MRC-5 cell lines were cultured in RPMI-1640 and treated with or without salermide...

Journal: :Biophysica 2021

The purpose of the study was to compare cytotoxicity two Quillaja saponaria bark saponin (QBS) mixtures against lung cell lines: normal MRC-5 fibroblast line and tumor A-549 epithelial cells lungs’ alveoli. study, performed both at a macro-scale in dedicated microfluidic device, showed that QBS more toxic abundant cholesterol (MRC-5). mixture with higher fraction found be cytotoxic towards line...

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