In the mouse strain GR, the Mtv-2 gene controls the expression of large amounts of mammary tumor virus (MTV) antigens in the milk at first lactation. It also controls the early appearance of mammary tumors. We have investigated the number of MTV proviral sequences associated with this Mtv-2 gene by nucleic acid hybridization between MTV [(3)H]cDNA and DNA from GR, B10, and GR-Mtv-2(-) mice. B10...

Video and music clips in MTV match together in particular ways to produce attractive effect. In this paper, we use a dual-wing harmonium model to learn and represent the underlying association patterns between music and video clips in professional MTV. We also use the discovered patterns to facilitate automatic MTV generation. Provided with a raw video and certain professional MTV as template, ...

BACKGROUND Tumor to normal tissue ratio (T/N ratio) on 11C-methionine (11C-MET) positron emission tomography/computed tomography (PET/CT) is affected by variable factors. We investigated whether T/N ratio cutoff values corrected according to metabolic tumor volume (MTV) could improve the diagnostic performance of 11C-MET PET/CT for diagnosis of recurrence in patients with metastatic brain tumor...

years; antisera from rabbits, rats, and guinea pigs immunized with MTV-containing tissue extracts are capable of neutralizing the biologic activity of the virus (1, 2, 3, 6, 9). More recently, it has been demonstrated that MTV is also immunogenic in the mouse; antisera from immunized mice react with MTV antigen in immunodiffusion to produce a precipitate line specific for MTV (5, 11). The prese...

We have previously reported new Mtv loci, Mtv-48 and -51, in the Japanese laboratory mouse strains CS and NC. Here we show by backcross analysis that both Mtv-48 and -51 cosegregate with very slow deletion of T cells bearing V beta 2. The nucleotide sequences of the open reading frames in the 3' long terminal repeats of Mtv-48 and -51 were very similar to those of Mtv-DDO, mouse mammary tumor v...

We report the construction of 17 recombinant inbred (RI) strains of mice derived from the progenitor strains NZB/BINRe and SM/J and the typing of this RI strain set, designated NXSM, for 58 loci distributed on 16 autosomes and the X chromosome. Two backcrosses involving NZB/BINJ and SM/J were constructed to confirm chromosomal assignments and determine gene orders suggested from NXSM RI strain ...

BACKGROUND The purpose of this study was to elucidate the prognostic significance of the pretreatment metabolic tumor volume (MTV) in patients with piriform sinus carcinoma treated by radiation-based therapy. METHODS This retrospective study included 100 patients with piriform sinus carcinomas who had received treatment by radiation-based therapy. The MTV values were obtained from pretreatmen...

Cellular immunity to mouse mammary tumor virus (MTV) in normal virgin female C3H/HeN-MTV+ (hereafter called C3H+) and C3H/HeN-MTV(hereafter called C3H-) mice was assessed by the indirect agarose droplet migration inhibition (Ml) assay. Spleen cells from C3H+ mice were able to respond to MTV antigens and produced a factor (presumably macrophage Ml factor) that inhibited migra tion of normal mous...

PURPOSE To evaluate the predictive and prognostic value of pretreatment metabolic tumor volume (MTV) in patients with treated by radiotherapy (RT) or concurrent chemoradiotherapy (CCRT). METHODS We reviewed the records of 118 patients with newly diagnosed laryngeal carcinoma, who had been treated by RT or CCRT. Pretreatment positron emission tomography (PET) was performed, and MTV values were...

Immune activation in murine AIDS (MAIDS) has been suggested to involve a superantigen (SAG). The possibility that SAGs encoded by mammary tumor virus (MTV) might be the source of stimulation was studied by using Mtv mice. Mtv- mice developed typical MAIDS, excluding a requirement for Mtv-encoded SAGs in the pathogenesis of this disorder.