BACKGROUND Recurrence risks for familial congenital anomalies in successive pregnancies are known, but this information for major structural anomalies is lacking. We estimated the absolute and relative risks of recurrent congenital anomaly in the second pregnancy for women with a history of a congenital anomaly in the first pregnancy, for all major anomaly groups and subtypes. METHODS Populat...

OBJECTIVES To evaluate the risk of major congenital anomaly associated with first-trimester exposure to insulin analogues compared with human insulin in offspring of women with pregestational diabetes. DESIGN AND SETTING A population-based cohort of women with pregestational diabetes (n=1661) who delivered between 1996 and 2012 was established retrospectively from seven European regions cover...

bortion has been legalized in Nepal since September 2002 by the 11 amendment to the "Muluki Ain". As per the law, the woman can procure abortion if she wishes, for any pregnancy up to 12 weeks of gestation, and up to 18 weeks if the pregnancy follows rape or incest. Abortion can be done if the fetus has a major congenital anomaly incompatible with life. Abortion can be done if continuation of p...

Background and aims: Congenital anomalies are as the major causes of stillbirths, neonatal death, disability and childhood health problems all over the world. The aim of this study was to determine the incidence and pattern of congenital anomalies in newborn during the first 24 hours of life in Shahid-Madani hospital, Azarshahr, Tabriz, during two periods 2002-2003 and 2...

Background: The aims were to determine the diagnostic accuracy of ultrasound sonography in detecting major structural anomalies on all patients who conceived during a year of infertility treatment [assisted reproductive technology (ART) or non-ART treatments] at the Royan Institute, and to study the outcome of cases with nuchal translucency (NT) ≥ 95th centile in the first trimester of pregnanc...

background and aims: congenital anomalies are as the major causes of stillbirths, neonatal death, disability and childhood health problems all over the world. the aim of this study was to determine the incidence and pattern of congenital anomalies in newborn during the first 24 hours of life in shahid-madani hospital, azarshahr, tabriz, during two periods 2002-2003 and 2012-2013 years. methods:...

SUMMARY Antenatal ultrasonography has an important rule in diagnosis of congenital malformation. At present identification of most major congenital abnormality during pregnancy depends on . sensitivity and resolution of the instrument, skilful and experienced sonologist and gestational age. Cranial and spinal defects and other malformations can be ferquently diagnosed with ultrasound. Major a...

The importance of identifying this anomaly is that it is associated with other congenital malformations in over 20% of cases, most commonly being associated with cardiovascular anomalies and congenital dislocation of hip. Of the 44 infants with this syndrome, Pape and Pickering found 27 to have major anomaly of skeletal, genitourinary, respiratory and cardiovascular systems. The disorder most c...

background: stillbirth is a sensitive indicator for health care quality, living conditions and equity in a society. the aim of this study was to determine the rate and contributing factors of stillbirth at babol hospitals. methods: this cross-sectional, descriptive, analytical study was designed as an applied research, using census sampling in 2012-2013. a questionnaire was applied for data col...